Markelova V F, Zalesskaia Iu M
Vopr Pitan. 1977 Jan-Feb(1):17-22.
Tests conducted with rats demonstrated that rations carrying saccharose cause a rise in the pre-beta-lipoproteids, blood triglycerides, total lipids and triglycerides in the aorta, as well as an accelerated biosynthesis of the latter in the liver and the fatty tissue. The effect of the saccharose making part of an isocaloric ration depends upon the quality of the diet as a whole. In rats receiving saccharose in a ration with a reduced amount of fat (11% bythe calorific value) there takes place an accelerated biosynthesis of phospholipids with no evidence of fatty degeneration of the liver. Animals receiving saccharose in a ration with a physiological level of fat (26% by caloricity) demonstrated a higher content of beta-lipoproteids in the blood, of total lipids and tryglycerides in the liver with lacking acceleration of the phospholipids biosynthesis in the latter.
对大鼠进行的试验表明,含有蔗糖的日粮会导致前β-脂蛋白、血液甘油三酯、总脂质以及主动脉中的甘油三酯升高,同时肝脏和脂肪组织中甘油三酯的生物合成加速。蔗糖作为等热量日粮的一部分所产生的影响取决于整个日粮的质量。在摄入脂肪含量降低(按热量值计算为11%)的日粮中含有蔗糖的大鼠中,磷脂的生物合成加速,且没有肝脏脂肪变性的迹象。在摄入脂肪含量处于生理水平(按热量计算为26%)的日粮中含有蔗糖的动物,血液中β-脂蛋白、肝脏中总脂质和甘油三酯的含量较高,而后者中磷脂的生物合成没有加速。