Wolfovitch R, Perl M
Biochem J. 1972 Dec;130(3):819-23. doi: 10.1042/bj1300819.
It was shown that cycloheximide inhibits CO(2) fixation in Euglena cells in the dark, but no effect of chloramphenicol was found. The light-dependent CO(2) fixation was inhibited by chloramphenicol and by large amounts of cycloheximide, but was stimulated by small amounts of cycloheximide. The presence of the stimulatory concentration of cycloheximide abolished the inhibition effect of high concentrations of chloramphenicol. The results indicate that the light-dependent CO(2) fixation is controlled by a repression-derepression regulatory system, which seems to be independent of chlorophyll synthesis.
结果表明，放线菌酮在黑暗中抑制眼虫细胞中的二氧化碳固定，但未发现氯霉素有此作用。氯霉素和大量放线菌酮可抑制光依赖型二氧化碳固定，但少量放线菌酮却能刺激其进行。刺激浓度的放线菌酮的存在消除了高浓度氯霉素的抑制作用。结果表明，光依赖型二氧化碳固定受一种阻遏-去阻遏调节系统控制，该系统似乎与叶绿素合成无关。
