糖尿病酮症酸中毒时高淀粉酶血症和腹痛的意义
Significance of hyperamylasaemia and abdominal pain in diabetic ketoacidosis.
作者信息
Knight A H, Williams D N, Ellis G, Goldberg D M
出版信息
Br Med J. 1973 Jul 21;3(5872):128-31. doi: 10.1136/bmj.3.5872.128.
Abstract
An analysis of 35 consecutive episodes of diabetic ketoacidosis confirmed the frequent high levels of serum amylase in this condition. Serum amylase was raised during 21 episodes (60%), and in six instances (17%) the peak level exceeded 1,000 Somogyi units per 100 ml. Hyperamylasaemia was more often found when the initial blood sugar exceeded 500 mg/100 ml, or when the onset of the episode had been relatively acute (less than 48 hours). There was no conclusive evidence in any patient to support a diagnosis of acute pancreatitis and other explanations for the hyperamylasaemia are discussed. Even grossly raised amylase levels were not associated with increased mortality or morbidity.
摘要
对35例连续性糖尿病酮症酸中毒病例的分析证实，在此病症中血清淀粉酶水平常常偏高。21例（60%）病例的血清淀粉酶升高，6例（17%）的峰值水平超过每100毫升1000索莫吉单位。当初始血糖超过500毫克/100毫升，或者病症发作相对急性（少于48小时）时，更常出现高淀粉酶血症。没有任何患者有确凿证据支持急性胰腺炎的诊断，文中讨论了高淀粉酶血症的其他解释。即便淀粉酶水平大幅升高也与死亡率或发病率增加无关。
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