Ashe J R, Schofield F A, Gram M R
Am J Clin Nutr. 1979 Feb;32(2):286-91. doi: 10.1093/ajcn/32.2.286.
Vitamin and mineral supplementation is often prescribed by physicians to meet the additional nutrient requirements of pregnancy. In order to partially ascertain the effectiveness of these prenatal supplements, the retention of calcium and iron was determined in pregnant women consuming supplemented or unsupplemented self-selected diets. The retention of phosphorus and magnesium, minerals not included in the prenatal supplements, was also determined. Seven-day metabolic balance experiments spaced periodically throughout the pregnancy were conducted on 10 healthy pregnant white women. The retention of calcium by the supplemented group was comparable to that of the unsupplemented group, while the retention of iron was more dependent on the magnitude of the iron intake than on its source. Although no supplement contained phosphate, the intake of phosphorus met the recommended allowances for this mineral. Significantly related to the intake of dietary calcium, the adequate phosphorus intakes reflected diets providing adequate calcium. The mean magnesium intake was only 60% of the recently established recommended dietary allowance. Although the calcium and iron salts provided by the prenatal supplements were well utilized, the intakes of phosphorus and magnesium indicate that the reliance on the effectiveness of mineral supplements should not lessen the emphasis by the physician on the importance of a good prenatal diet.
医生通常会开具维生素和矿物质补充剂,以满足孕期额外的营养需求。为了部分确定这些产前补充剂的有效性,对食用补充或未补充自选饮食的孕妇进行了钙和铁潴留量的测定。同时也测定了磷和镁(产前补充剂中未包含的矿物质)的潴留量。对10名健康的白人孕妇在孕期定期进行了为期7天的代谢平衡实验。补充组的钙潴留量与未补充组相当,而铁潴留量更多地取决于铁摄入量的多少,而非其来源。尽管没有补充剂含有磷酸盐,但磷的摄入量达到了该矿物质的推荐摄入量。与膳食钙摄入量显著相关,充足的磷摄入量反映了提供充足钙的饮食。平均镁摄入量仅为最近确定的推荐膳食摄入量的60%。尽管产前补充剂提供的钙盐和铁盐得到了很好的利用,但磷和镁的摄入量表明,依赖矿物质补充剂的有效性不应减轻医生对优质产前饮食重要性的强调。