Salganik R I, Seliatitskaia V G, Shorin Iu P
Ontogenez. 1979;10(6):625-9.
The cooling of new born rats within the first 7 days of life (15 min, +2--+4 degrees) was shown to lead to stable hormonal changes in their adult state (4 to 5 months): the content of corticosterone and insulin in blood increased twice. The short cooling of adult rats resulted in the increase of trioiodothyronine content and decrease of insulin content in blood and the increased induction of tyrosine aminotransferase in the liver. The data obtained corroborate an idea that the induction of certain biochemical processes during early postnatal period, due to the involvement in the transcription of certain genes, leads to stable changes in the spectrum of metabolic processes and reactions.
新生大鼠在出生后7天内进行冷却（15分钟，+2至+4摄氏度），结果表明会导致其成年状态（4至5个月）出现稳定的激素变化：血液中皮质酮和胰岛素的含量增加了两倍。成年大鼠的短期冷却导致血液中三碘甲状腺原氨酸含量增加、胰岛素含量降低，以及肝脏中酪氨酸转氨酶的诱导增加。所获得的数据证实了这样一种观点，即由于某些基因参与转录，出生后早期某些生化过程的诱导会导致代谢过程和反应谱的稳定变化。
