Kelkar S S, Niphadkar K B, Khare P M, Junnarkar R V
Bull World Health Organ. 1973 May;48(5):555-8.
A survey of hospital patients with lepromatous and with tuberculoid leprosy showed 5% of the former and 6.3% of the latter to be carriers of hepatitis B antigen. These findings contradict the hypothesis of a genetically determined predisposition; opportunity for infection appears rather to be the determining factor. It was also found that (1) the number of carriers was higher among patients staying longer in hospital; (2) titres of antigen in patients with lepromatous leprosy were higher than in those with tuberculoid leprosy or in controls; and (3) antigen titres measured twice at an interval of 4 months indicated that the carrying of hepatitis B antigen in patients with leprosy is stable and persistent.
一项针对瘤型麻风病患者和结核样型麻风病患者的调查显示,前者中有5%、后者中有6.3%为乙肝抗原携带者。这些发现与遗传易感性假说相矛盾;感染机会似乎才是决定性因素。还发现:(1)住院时间较长的患者中携带者数量较多;(2)瘤型麻风病患者的抗原滴度高于结核样型麻风病患者或对照组;(3)间隔4个月进行两次测量的抗原滴度表明,麻风病患者携带乙肝抗原的情况稳定且持续。