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[麻风病中的“e”抗原(HBeAg)]

[The "e" antigen (HBeAg) in leprosy].

作者信息

Nuti M, Tarabini G C, Tarabini G C, Thamer G

出版信息

Quad Sclavo Diagn. 1977 Dec;13(4):393-403.

PMID:614601
Abstract

Sixty-six sera from leprosy patients, 42 with lepromatous leprosy (l.l.) and 24 with tuberculoid leprosy (t.l.) were examinated for the presence of e-antigen and e-antibody by immunodiffusion. The test for e-antigen was negative in all leprosy patients; e-antibodies were found in only three patients (4.5%) with l.l., all carriers of hepatitis B antigen. The HBsAg test was positive in 23.8% of the l.l. cases and in 12.5% of the t.l. cases; the anti-HBs was present in 38.1% of the l.l. cases and in 41.6% of the t.l. cases. The results suggest the possibility that the leprosy patients positive for the surface B antigen represent a very low risk and can be considered as chronic asymptomatic carriers of HBsAg.

摘要

采用免疫扩散法对66份麻风病人血清进行检查,其中42份为瘤型麻风(l.l.)血清,24份为结核样型麻风(t.l.)血清,以检测e抗原和e抗体的存在情况。所有麻风病人的e抗原检测均为阴性;仅在3例(4.5%)瘤型麻风病人中发现e抗体,这些病人均为乙肝抗原携带者。瘤型麻风病例中23.8%的HBsAg检测呈阳性,结核样型麻风病例中12.5%的检测呈阳性;抗-HBs在瘤型麻风病例中的出现率为38.1%,在结核样型麻风病例中的出现率为41.6%。结果提示,乙肝表面抗原阳性的麻风病人代表的风险极低,可被视为HBsAg的慢性无症状携带者。

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