Nuti M, Tarabini G C, Tarabini G C, Thamer G
Quad Sclavo Diagn. 1977 Dec;13(4):393-403.
Sixty-six sera from leprosy patients, 42 with lepromatous leprosy (l.l.) and 24 with tuberculoid leprosy (t.l.) were examinated for the presence of e-antigen and e-antibody by immunodiffusion. The test for e-antigen was negative in all leprosy patients; e-antibodies were found in only three patients (4.5%) with l.l., all carriers of hepatitis B antigen. The HBsAg test was positive in 23.8% of the l.l. cases and in 12.5% of the t.l. cases; the anti-HBs was present in 38.1% of the l.l. cases and in 41.6% of the t.l. cases. The results suggest the possibility that the leprosy patients positive for the surface B antigen represent a very low risk and can be considered as chronic asymptomatic carriers of HBsAg.
采用免疫扩散法对66份麻风病人血清进行检查，其中42份为瘤型麻风（l.l.）血清，24份为结核样型麻风（t.l.）血清，以检测e抗原和e抗体的存在情况。所有麻风病人的e抗原检测均为阴性；仅在3例（4.5%）瘤型麻风病人中发现e抗体，这些病人均为乙肝抗原携带者。瘤型麻风病例中23.8%的HBsAg检测呈阳性，结核样型麻风病例中12.5%的检测呈阳性；抗-HBs在瘤型麻风病例中的出现率为38.1%，在结核样型麻风病例中的出现率为41.6%。结果提示，乙肝表面抗原阳性的麻风病人代表的风险极低，可被视为HBsAg的慢性无症状携带者。
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