Tanay A, Yust I, Peresecenschi G, Abramov A L, Aviram A
Ann Intern Med. 1979 Jan;90(1):50-2. doi: 10.7326/0003-4819-90-1-50.
A 68-year-old patient with the syndrome of inappropriate antidiuretic hormone secretion secondary to basilary skull fracture was treated successfully with demeclocycline and phenytoin. Phenytoin, which was considered in the past only as a useful diagnostic tool, was given to the patient on a long-term basis. The drug reversed the patient's symptoms and abnormal laboratory values to normal limits without adverse reactions during a treatment period of 8 months.
一名68岁因颅底骨折继发抗利尿激素分泌异常综合征的患者，经地美环素和苯妥英治疗成功。苯妥英过去仅被视为一种有用的诊断工具，现给予该患者长期使用。在8个月的治疗期间，该药使患者的症状和异常实验室检查值恢复到正常范围，且无不良反应。
