• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利：CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法，用中文像聊天一样搜索，搜遍4000万医学文献。AI智能推荐，让科研检索更轻松。

立即免费搜索

文件翻译

保留排版，准确专业，支持PDF/Word/PPT等文件格式，支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述，25分钟生成高质量综述，智能提取关键信息，辅助科研写作。

立即免费体验

采用化学电离质谱法筛查尿液中的有机酸。

Screening of organic acids in urine by chemical ionization mass spectrometry.

作者信息

Issachar D, Yinon J

出版信息

Biomed Mass Spectrom. 1979 Feb;6(2):47-56. doi: 10.1002/bms.1200060203.

DOI:10.1002/bms.1200060203
PMID:420910
Abstract

A method has been developed for qualitative screening of carboxylic acids in human urine. The method uses direct chemical inoization mass spectrometry with isobutane as reagent gas. The carboxylic acids are separated from the urine samples by ion exchange. Normal carboxylic acid profiles have been determined and are compared with the profiles of patients suffering from certain metabolic disorders.

摘要

已开发出一种用于定性筛查人尿中羧酸的方法。该方法采用以异丁烷作为反应气的直接化学电离质谱法。通过离子交换将羧酸从尿液样本中分离出来。已确定了正常羧酸谱，并与患有某些代谢紊乱疾病患者的谱进行了比较。

相似文献

1
Screening of organic acids in urine by chemical ionization mass spectrometry.采用化学电离质谱法筛查尿液中的有机酸。
Biomed Mass Spectrom. 1979 Feb;6(2):47-56. doi: 10.1002/bms.1200060203.
2
Diagnosis of disorders in amino acid methabolism by chemical ionization mass spectrometry.通过化学电离质谱法诊断氨基酸代谢紊乱
Clin Chim Acta. 1976 Dec 1;73(2):307-14. doi: 10.1016/0009-8981(76)90177-7.
3
Simultaneous retention index analysis of urinary amino acids and carboxylic acids for graphic recognition of abnormal state.
J Chromatogr B Analyt Technol Biomed Life Sci. 2005 Jul 5;821(1):94-104. doi: 10.1016/j.jchromb.2005.04.011.
4
A rapid ultra performance liquid chromatography tandem mass spectrometric method for measuring amino acids associated with maple syrup urine disease, tyrosinaemia and phenylketonuria.一种用于测定与枫糖尿症、酪氨酸血症和苯丙酮尿症相关氨基酸的快速超高效液相色谱串联质谱法。
Ann Clin Biochem. 2007 Sep;44(Pt 5):474-81. doi: 10.1258/000456307781646012.
5
[Methodology in the study of organic acids in children].[儿童有机酸研究中的方法学]
C R Seances Soc Biol Fil. 1982;176(1):30-8.
6
New conjugated urinary metabolites in intermediate type maple syrup urine disease.
Clin Chim Acta. 1987 Oct 30;169(1):77-83. doi: 10.1016/0009-8981(87)90395-0.
7
Screening newborns for multiple organic acidurias in dried filter paper urine samples: method development.利用干滤纸尿样筛查新生儿多种有机酸尿症：方法开发
Pediatr Res. 1991 Oct;30(4):315-21. doi: 10.1203/00006450-199110000-00005.
8
Use of a diode array detector in investigation of neonatal organic aciduria.
Clin Chem. 1985 Apr;31(4):561-3.
9
Determination of organic acids in urine by solid-phase microextraction and gas chromatography-ion trap tandem mass spectrometry previous 'in sample' derivatization with trimethyloxonium tetrafluoroborate.通过固相微萃取和气相色谱-离子阱串联质谱法，并在样品中预先用四氟硼酸三甲氧鎓进行衍生化来测定尿液中的有机酸。
Biomed Chromatogr. 2008 Oct;22(10):1155-63. doi: 10.1002/bmc.1039.
10
Detection of inherited metabolic disorders via tandem mass spectrometry in Thai infants.泰国婴儿中通过串联质谱法检测遗传性代谢疾病。
Southeast Asian J Trop Med Public Health. 1999;30 Suppl 2:154-9.