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[大鼠血小板因子 XIII 及其在血小板聚集中的作用]

[Rat thrombocyte factor XIII and its role in platelet aggregation].

作者信息

Pastorova V E, Umarova B A, Sukhanova S A

出版信息

Biull Eksp Biol Med. 1979 Feb;87(2):99-101.

PMID:420942
Abstract

Factor XIII was isolated from rat platelets; it activity was 1430 units per 1 mg of protein. It was shown in experiments in vitro that addition of this factor (160--200 units/ml) to the suspension of washed platelets or those purified by passage through the column with sepharose 4B increased their aggregation capacity. Addition of inactive platelet factor XIII failed to influence the platelet aggregation induced by ADP.

摘要

凝血因子XIII是从大鼠血小板中分离出来的;其活性为每1毫克蛋白质1430单位。体外实验表明,向洗涤过的血小板悬液或通过琼脂糖4B柱纯化的血小板悬液中添加该因子(160 - 200单位/毫升)可提高其聚集能力。添加无活性的血小板凝血因子XIII对ADP诱导的血小板聚集没有影响。

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1
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