Makey D A, Tovey F I, Heald R J
Br J Surg. 1979 Jan;66(1):39-42. doi: 10.1002/bjs.1800660112.
One hundred and seventy-three underwent proximal gastric vagotomy for duodenal ulceration over a 6-year period. One hundred and fifteen of these have been followed up for 1-5 years. The operative mortality was nil and the result was satisfactory in 91 per cent. The incidence of side effects was small, notably that of dumping being 2.4 per cent and of diarrhoea, 3.6 per cent. Incidence of postoperative heartburn was reduced from 13 per cent to 4 per cent by the introduction of hepatic interposition. The incidence of recurrent ulceration was 5.1 per cent after an average interval of 2 years and that of new gastric ulceration 2.6 per cent after an average of 4 years. There were no recurrent ulcers in those who had peroperative Burge tests, although secretory studies showed no difference between those tested and those not tested. Most recurrences occurred in the earliest cases operated on before Burge testing was introduced and when only 2 cm of the lower oesophagus were exposed.
在6年期间，173例因十二指肠溃疡接受了近端胃迷走神经切断术。其中115例已随访1至5年。手术死亡率为零，91%的结果令人满意。副作用发生率较低，倾倒综合征发生率为2.4%，腹泻发生率为3.6%。通过采用肝间置术，术后烧心的发生率从13%降至4%。平均间隔2年后，复发性溃疡的发生率为5.1%，平均4年后新发性胃溃疡的发生率为2.6%。接受术中Burge试验的患者未出现复发性溃疡，尽管分泌研究显示接受试验者与未接受试验者之间无差异。大多数复发发生在引入Burge试验之前最早接受手术的病例中，当时仅暴露2厘米的食管下段。
