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血压临界升高的年轻男性的颈动脉压力反射功能

Carotid baroreflex function in young men with borderline blood pressure elevation.

作者信息

Eckberg D L

出版信息

Circulation. 1979 Apr;59(4):632-6. doi: 10.1161/01.cir.59.4.632.

DOI:10.1161/01.cir.59.4.632
PMID:421303
Abstract

Carotid baroreflex function was assessed in 10 normotensive young men and 20 age-matched subjects with borderline hypertension (successive blood pressures above and below 140/90 mm Hg) by measuring sinus node responses to brief neck suction. Subjects with borderline hypertension were divided into two equal groups according to their average systolic arterial pressures. Baroreflex responses were reset to function at higher pressure levels than normal in subjects with mild borderline hypertension, but reflex sensitivity was normal. Responses were also reset in subjects with more severe borderline hypertension, but reflex was subnormal. The results suggest that a gradation of baroreflex responsiveness exists among patients classified as having borderline hypertension: Subnormal responsiveness was found in those subjects whose resting average systolic arterial pressure was greater than or equal to 140 mm Hg.

摘要

通过测量窦房结对短暂颈部负压吸引的反应,对10名血压正常的年轻男性和20名年龄匹配的临界高血压受试者(连续血压高于和低于140/90毫米汞柱)的颈动脉压力反射功能进行了评估。临界高血压受试者根据其平均收缩压被分为两组,每组人数相等。轻度临界高血压受试者的压力反射反应被重新设定为在比正常更高的压力水平下起作用,但反射敏感性正常。重度临界高血压受试者的反应也被重新设定,但反射功能低于正常水平。结果表明,在被归类为临界高血压的患者中存在压力反射反应性的分级:在静息平均收缩压大于或等于140毫米汞柱的受试者中发现反应性低于正常水平。

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