家族性甲状腺素结合球蛋白缺乏症：与Xg血型的连锁研究
Familial thyroxine-binding globulin deficiency: search for linkage with Xg blood groups.
作者信息
Grant D B, Clarke H G, Putman D
出版信息
J Med Genet. 1974 Sep;11(3):271-4. doi: 10.1136/jmg.11.3.271.
Abstract
Serum thyroxine-binding globulin (TBG), thyroxine, and thyrotrophin were estimated in members of a family with TBG deficiency. Xg red cell antigen status was also studied. TBG deficiency appeared to be inherited as an X-linked condition. Four male members of the family showed absent TBG and seven heterozygous women showed intermediate TBG levels. Five informative phase known members of the family showed no recombination between and
摘要
对一个患有甲状腺素结合球蛋白（TBG）缺乏症的家族成员进行了血清甲状腺素结合球蛋白、甲状腺素和促甲状腺激素的检测。还研究了Xg红细胞抗原状态。TBG缺乏症似乎是以X连锁的方式遗传的。该家族的四名男性成员显示TBG缺失，七名杂合子女性显示TBG水平处于中间值。该家族五名已知信息阶段的成员显示在……之间没有重组。
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