Schulze K, Mitros F A
Dis Colon Rectum. 1979 Jan-Feb;22(1):47-50. doi: 10.1007/BF02586758.
Eosinophilic gastroenteritis, an idiopathic inflammation of the alimentary canal, is characterized by infiltration of the intestinal wall by eosinophils, massive submucosal edema, and peripheral eosinophilia. It is generally confined to the gastric antrum and proximal small intestine. A young woman had an eosinophilic infiltrate that involved the distal ileum and right colon only. Barium studies showed severe narrowing and shortening of the cecum and ascending colon. Symptoms of intestinal obstruction did not respond satisfactorily to conservative measures. Adhesions over the ileocecal area as well as thickening and induration of the terminal ileum and proximal right colon were found on hemicolectomy. The remaining intestine and the peritoneal cavity were felt to be normal. Histologic examination showed a cellular infiltrate with prominent eosinophils in the mucosa, submucosal edema and fibrosis. During a 40-month follow-up period after the hemicolectomy, the patient has not shown clear evidence of recurrence or extension of the disease to the stomach or proximal small intestine. It is concluded that idiopathic eosinophilic gastroenteritis may primarily involve the ileocecal area. In that location it must be specifically differentiated from intestinal tuberculosis, amebiasis, and Crohn's disease.
嗜酸性粒细胞性胃肠炎是一种消化道的特发性炎症，其特征为嗜酸性粒细胞浸润肠壁、大量黏膜下水肿和外周嗜酸性粒细胞增多。它通常局限于胃窦和近端小肠。一名年轻女性的嗜酸性粒细胞浸润仅累及回肠末端和右结肠。钡剂检查显示盲肠和升结肠严重狭窄和缩短。肠梗阻症状对保守治疗反应不佳。半结肠切除术中发现回盲部区域有粘连以及回肠末端和近端右结肠增厚和硬结。其余肠道和腹膜腔被认为正常。组织学检查显示黏膜有以嗜酸性粒细胞为主的细胞浸润、黏膜下水肿和纤维化。在半结肠切除术后40个月的随访期内，患者未表现出疾病复发或蔓延至胃或近端小肠的明确证据。结论是，特发性嗜酸性粒细胞性胃肠炎可能主要累及回盲部区域。在该部位，它必须与肠结核、阿米巴病和克罗恩病进行明确鉴别。
