Lapointe G, Nosal G
Experientia. 1979 Feb 15;35(2):205-7. doi: 10.1007/BF01920618.
The neurobehavioral evolution of the normally growing rat has been investigated by means of a series of reflex, motor and sensory tests from birth up to weaning. A sequential development of behavioral responses has been assessed over this 21-days period, and 2nd week following birth representing an important step in the neurobehavioral maturation of the rat. This rat model may be considered as an useful reference to evaluate changes that may be induced by pharmacological and toxicological agents in the developing exposed rat.
通过一系列从出生到断奶的反射、运动和感觉测试,对正常生长大鼠的神经行为发育进行了研究。在这21天的时间里评估了行为反应的顺序发展,出生后的第二周是大鼠神经行为成熟的重要阶段。该大鼠模型可被视为评估发育中暴露大鼠体内药物和毒理学制剂可能引起的变化的有用参考。