Floeter M K, Greenough W T
Science. 1979 Oct 12;206(4415):227-9. doi: 10.1126/science.113873.
Dendritic branching in Purkinje and granule cells and the diameters of Purkinje cell somas were compared in several cerebellar areas of monkeys reared in isolation, with social experience, or in a large colony. In the colony-reared monkeys, spiny branchlets of Purkinje cells were more extensive in the paraflocculus and the nodulus than they were in the other two groups. Granule cell dendritic branching in the paraflocculus and nodulus did not differ across groups. In addition, Purkinje cell somas were larger in the uvula and the nodulus of the colony animals than in the other groups. These data indicate that the social and physical environment during development influences the morphology of cerebellar Purkinje cells.
在单独饲养、有社交经历或饲养在大群体中的猴子的几个小脑区域，对浦肯野细胞和颗粒细胞的树突分支以及浦肯野细胞胞体的直径进行了比较。在群体饲养的猴子中，浦肯野细胞的棘状小分支在旁绒球和小结中比在其他两组中更广泛。不同组间颗粒细胞在旁绒球和小结中的树突分支没有差异。此外，群体饲养动物的蚓垂和小结中的浦肯野细胞胞体比其他组的更大。这些数据表明，发育过程中的社会和物理环境会影响小脑浦肯野细胞的形态。
