Fedorova G I, Podcherniaeva R Ia, Amchenkova A M, Nikitina N I, Blinova V K
Tsitol Genet. 1974 Sep-Oct;8(5):396-9.
When the Drosophila cells were infected with the mixo- and arboviruses, in case of influenza A/WSN virus a rise in the titre and slight cytopathogenic effect with the subsequent decrease in the titre was observed. Since the decrease in the virus titer was not observed when actinomycin D was added, it was supposed that interferonlike inhibitor may be produced by the infected cells. Vacuolization and increase in the size of the infected cells were caused by all the nuclear polyhedrosis viruses tested. The number of the infected cells depended on the virus type and multiplicity of the infection.
当果蝇细胞感染混合病毒和虫媒病毒时，对于甲型流感病毒A/WSN株，观察到病毒滴度先升高，伴有轻微细胞病变效应，随后病毒滴度下降。由于添加放线菌素D后未观察到病毒滴度降低，因此推测受感染细胞可能产生了类干扰素抑制剂。所有测试的核型多角体病毒都会导致受感染细胞出现空泡化和细胞大小增加。受感染细胞的数量取决于病毒类型和感染复数。
