Brown H D, Chattopadhyay S K, Patel A B
Science. 1967 Sep 29;157(3796):1577-8. doi: 10.1126/science.157.3796.1577.
Erythrocyte ghosts isolated from myopathic patients responded to 10(-4) molar ouabain with a dramatic increase in adenosine triphosphatase activity, while identical preparations from normal donors were inhibited by the same drug. These results have been interpreted in terms of a disease-related change in membrane integrity bearing upon function of the transport enzyme.
从患有肌病的患者身上分离出的红细胞血影对10⁻⁴摩尔的哇巴因产生反应，其腺苷三磷酸酶活性急剧增加，而来自正常供体的相同制剂则受到同一药物的抑制。这些结果已根据与疾病相关的膜完整性变化对转运酶功能的影响进行了解释。
