Goedde H W, Benkmann H G, Das P K, Agarwal D P
Klin Wochenschr. 1977 Mar 1;55(5):215-7. doi: 10.1007/BF01487713.
Activity of creatine kinase isoenzyme MB in serum and variants of red cell acetylcholinesterase were determined in patients with Duchenne muscular dystrophy, in other forms of Dystrophy and in family members of Duchenne patients and healthy controls. Creatine kinase isoenzyme MB was observed only in all cases of DMD as well as variants of red cell acetylcholinesterase characterized by so-called inhibitor numbers. Carriers of Duchenne muscular dystrophy can be distinguished from Duchenne patients and healthy controls by estimation of Acetylcholinesterase variants.
对杜氏肌营养不良症患者、其他形式的肌营养不良症患者、杜氏患者的家庭成员以及健康对照者测定了血清中肌酸激酶同工酶MB的活性和红细胞乙酰胆碱酯酶的变体。仅在所有杜氏肌营养不良症病例以及以所谓抑制剂数量为特征的红细胞乙酰胆碱酯酶变体中观察到肌酸激酶同工酶MB。通过评估乙酰胆碱酯酶变体，可将杜氏肌营养不良症携带者与杜氏患者及健康对照者区分开来。
