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血管扩张剂和脊髓切开术对大鼠急性脊髓损伤后恢复的影响。

Effect of vasodilators and myelotomy on recovery after acute spinal cord injury in rats.

作者信息

Rivlin A S, Tator C H

出版信息

J Neurosurg. 1979 Mar;50(3):349-52. doi: 10.3171/jns.1979.50.3.0349.

DOI:10.3171/jns.1979.50.3.0349
PMID:422987
Abstract

The effect of papaverine, nitroprusside, or myelotomy on the recovery of spinal cord function was studied in rats after acute cord-compression injury. Spinal cord recovery was measured by a quantitative method of clinical assessment previously developed in our laboratory. Neither papaverine nor nitroprusside improved recovery of cord function. Dorsal midline myelotomy extending anteriorly as far as the central canal did not produce significant improvement (p greater than 0.05). However, when the myelotomy extended completely through the cord in the anteroposterior plane significant improvement (p less than 0.01) was obtained.

摘要

在大鼠急性脊髓压迫损伤后,研究了罂粟碱、硝普钠或脊髓切开术对脊髓功能恢复的影响。脊髓恢复情况通过我们实验室先前开发的一种临床评估定量方法进行测量。罂粟碱和硝普钠均未改善脊髓功能的恢复。向前延伸至中央管的背侧中线脊髓切开术未产生显著改善(p>0.05)。然而,当脊髓切开术在前后平面完全贯穿脊髓时,则获得了显著改善(p<0.01)。

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Effect of vasodilators and myelotomy on recovery after acute spinal cord injury in rats.血管扩张剂和脊髓切开术对大鼠急性脊髓损伤后恢复的影响。
J Neurosurg. 1979 Mar;50(3):349-52. doi: 10.3171/jns.1979.50.3.0349.
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