Mitchell J A
J Morphol. 1979 Jan;159(1):67-80. doi: 10.1002/jmor.1051590106.
The distribution and morphology of phagocytic (Type II) supraependymal cells residing within the third ventricle of the guinea pig were investigated by scanning electron microscopy. Type II supraependymal cells were restricted to nonciliated regions of the ventricle. They were most numerous on the choroid plexus, abundant within the infundibular recess and were present on the ventricular floor in the region of the median eminence. Morphologically, they were characterized by a soma from which pseudopodia-like processes extended to the subjacent ependyma. Type II cells varied in configuration according to their location. Those residing on the choroid plexus typically had irregular somas and possessed processes that generally terminated in finger-like extensions. In contrast, cells on the ventricular floor and within the infundibular recess were stellate and possessed processes that terminated in fan-like cytoplasmic expansion. There were no differences noted in the frequency, distribution or morphology of Type II supraependymal cells in male and female animals. Furthermore, cell frequency did not appear to vary in relation to the estrous cycle. The data suggest that the pleomorphism exhibited by Type II supraependymal cells may reflect adaptations to diverse environmental conditions present within different regions of the third ventricle.
通过扫描电子显微镜研究了豚鼠第三脑室内吞噬性（II型）室管膜上细胞的分布和形态。II型室管膜上细胞局限于脑室的非纤毛区域。它们在脉络丛上最多，在漏斗隐窝内丰富，并存在于正中隆起区域的脑室底部。形态上，它们的特征是有一个胞体，从胞体伸出伪足样突起至相邻的室管膜。II型细胞根据其位置的不同而形态各异。位于脉络丛上的细胞通常有不规则的胞体，其突起一般末端呈指状延伸。相比之下，脑室底部和漏斗隐窝内的细胞呈星状，其突起末端呈扇形的细胞质扩张。在雄性和雌性动物中，II型室管膜上细胞的频率、分布或形态均未发现差异。此外，细胞频率似乎也不随发情周期而变化。数据表明，II型室管膜上细胞表现出的多形性可能反映了对第三脑室不同区域存在的不同环境条件的适应性。
