Marks S R, Elders M J
J Natl Med Assoc. 1979 Feb;71(2):153-9.
Precocious puberty can be very confusing and frightening to an affected child and his or her family. The following presentation includes the pertinent physiology, psychology, etiology, diagnosis, and treatment of precocious pubertal development. Radioimmunoassays for gonadotropins and several key hormones are now available which enable the clinician to evaluate and follow the patient's condition with confidence and expertise. Three drugs have been proven effective and the most recent one, cyproterone acetate, has produced exciting clinical remissions with virtually no known side effects.
性早熟对于患病儿童及其家庭来说可能会非常令人困惑和恐惧。以下内容包括性早熟发育的相关生理学、心理学、病因学、诊断和治疗。现在已有针对促性腺激素和几种关键激素的放射免疫测定法,这使临床医生能够自信且专业地评估和跟踪患者的病情。三种药物已被证明有效,而最新的一种药物醋酸环丙孕酮已产生了令人振奋的临床缓解效果,且几乎没有已知的副作用。