Lussier G, Pavilanis V
Can J Comp Med. 1968 Oct;32(4):533-8.
Wasting disease was observed in hamsters inoculated at birth with a cell-free bovine leukemic extract. The autopsy and histological examination of the runted hamsters revealed visible lesions in the lymphoid tissues. These lesions consisted mostly in depletion of lympocytes in the spleen and in the cortex of the lymph nodes and in atrophy of the Peper's patches. Thymic lesions were also observed. Anemia and a decrease of circulating lymphocytes were observed in the peripheral blood.
在出生时接种无细胞牛白血病提取物的仓鼠中观察到消瘦病。对发育不良的仓鼠进行尸检和组织学检查发现,淋巴组织有明显病变。这些病变主要表现为脾脏和淋巴结皮质中的淋巴细胞减少以及派伊尔氏小结萎缩。还观察到胸腺病变。在外周血中观察到贫血和循环淋巴细胞减少。