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[接种牛白血病物质后仓鼠产生的消瘦病]

[Wasting disease produced in hamsters after the inoculation of a bovine leukemic material].

作者信息

Lussier G, Pavilanis V

出版信息

Can J Comp Med. 1968 Oct;32(4):533-8.

PMID:4234784
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC1319294/
Abstract

Wasting disease was observed in hamsters inoculated at birth with a cell-free bovine leukemic extract. The autopsy and histological examination of the runted hamsters revealed visible lesions in the lymphoid tissues. These lesions consisted mostly in depletion of lympocytes in the spleen and in the cortex of the lymph nodes and in atrophy of the Peper's patches. Thymic lesions were also observed. Anemia and a decrease of circulating lymphocytes were observed in the peripheral blood.

摘要

在出生时接种无细胞牛白血病提取物的仓鼠中观察到消瘦病。对发育不良的仓鼠进行尸检和组织学检查发现,淋巴组织有明显病变。这些病变主要表现为脾脏和淋巴结皮质中的淋巴细胞减少以及派伊尔氏小结萎缩。还观察到胸腺病变。在外周血中观察到贫血和循环淋巴细胞减少。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0cff/1319294/948ba709c94f/compmed00071-0030-d.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0cff/1319294/43903746a4e3/compmed00071-0029-a.jpg
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https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0cff/1319294/cde4a70f7a4b/compmed00071-0029-c.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0cff/1319294/57fcd7e4b174/compmed00071-0029-d.jpg
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https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0cff/1319294/58a0f5b0ec9d/compmed00071-0030-b.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0cff/1319294/9f5abb2fa662/compmed00071-0030-c.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0cff/1319294/948ba709c94f/compmed00071-0030-d.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0cff/1319294/43903746a4e3/compmed00071-0029-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0cff/1319294/18bdec2376b8/compmed00071-0029-b.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0cff/1319294/cde4a70f7a4b/compmed00071-0029-c.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0cff/1319294/57fcd7e4b174/compmed00071-0029-d.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0cff/1319294/12f64310d578/compmed00071-0030-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0cff/1319294/58a0f5b0ec9d/compmed00071-0030-b.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0cff/1319294/9f5abb2fa662/compmed00071-0030-c.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0cff/1319294/948ba709c94f/compmed00071-0030-d.jpg

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1
[Wasting disease produced in hamsters after the inoculation of a bovine leukemic material].[接种牛白血病物质后仓鼠产生的消瘦病]
Can J Comp Med. 1968 Oct;32(4):533-8.
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引用本文的文献

1
Malignant lymphomas in hamsters following a wasting disease produced with bovine leukemic extract--a preliminary report.用牛白血病提取物引发消瘦病后仓鼠发生的恶性淋巴瘤——初步报告
Can J Comp Med. 1969 Jan;33(1):81-2.

本文引用的文献

1
Effects of a filtrable, self-propagating contaminant on a transplantable acute lymphoid leukemia in mice.一种可滤过、自我传播的污染物对小鼠可移植性急性淋巴细胞白血病的影响。
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Graft-versus-host reactions in the rabbit.兔的移植物抗宿主反应。
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COOMBS-POSITIVE HEMOLYTIC ANEMIA AND GENERALIZED AMYLOIDOSIS IN MICE FOLLOWING TRANSMISSION OF SUBCELLULAR LEUKEMIC MATERIAL.亚细胞白血病物质传播后小鼠的库姆斯阳性溶血性贫血和全身性淀粉样变性
Proc Soc Exp Biol Med. 1964 Aug-Sep;116:1154-9. doi: 10.3181/00379727-116-29478.
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THE ABSENCE OF WASTING IN THYMECTOMIZED GERMFREE (AXENIC) MICE.胸腺切除的无菌(单菌)小鼠无消瘦现象。
Proc Soc Exp Biol Med. 1964 Oct;117:237-9. doi: 10.3181/00379727-117-29545.
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PATHOGENESIS OF THE POST-NEONATAL THYMECTOMY WASTING SYNDROME.新生儿期后胸腺切除致消瘦综合征的发病机制
Nature. 1964 Oct 10;204:151-5. doi: 10.1038/204151a0.
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PATHOLOGIC CHANGES IN LYMPHOID TISSUES IN EARLY TRANSPLANTATION (RUNT) DISEASE IN MICE.小鼠早期移植( runt )病中淋巴组织的病理变化。
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BACTERIAL INFECTION AND WASTING IN NEONATALLY THYMECTOMIZED RATS.新生期切除胸腺大鼠的细菌感染与消瘦
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ATTEMPTS TO DEMONSTRATE A VIRUS FOR BOVINE LYMPHOSARCOMA.证明牛淋巴肉瘤病毒的尝试。
Am J Vet Res. 1964 May;25:668-78.
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WASTING DISEASE INDUCED IN YOUNG MICE BY ADMINISTRATION OF CORTISOL ACETATE.醋酸皮质醇诱导幼鼠消瘦症
Science. 1964 Feb 28;143(3609):965-6. doi: 10.1126/science.143.3609.965.
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RESEARCHES ON A VIRUS ISOLATED FROM A CALF AFFECTED WITH LYMPHATIC LEUKEMIA.
Ann N Y Acad Sci. 1963 Nov 4;108:1173-92. doi: 10.1111/j.1749-6632.1963.tb13443.x.