Kishimoto Y, Kawamura N
Mol Cell Biochem. 1979 Jan 15;23(1):17-25. doi: 10.1007/BF00226676.
Ceramide is the fundamental structure and key intermediate of all sphingolipids. Biosynthesis and catabolism of brain ceramide, especially their relationship to the metabolism of more complex sphingolipids in brain, are reviewed. Human genetic diseases which involve altered ceramide metabolism are also discussed.
神经酰胺是所有鞘脂的基本结构和关键中间体。本文综述了脑内神经酰胺的生物合成与分解代谢,尤其是它们与脑内更复杂鞘脂代谢的关系。文中还讨论了涉及神经酰胺代谢改变的人类遗传疾病。