Würsch P, Welsch C, Arnaud M J
Nutr Metab. 1979;23(3):145-55. doi: 10.1159/000176251.
L-[U-14C]-sorbose was administered orally as single doses to 5 normal rats. The recovery of radioactivity was 5.3% in the urine, 46% in the faeces exclusively as L-sorbose 16% as carbon dioxide. Caloric utilization was approximately 25%. A second group of 3 rats that had previously received L-sorbose in their diet showed 14C recoveries of 8.9% in the urine, 6.6% in the faeces and 59% as carbon dioxide. The time course of expired carbon dioxide suggests that a portion of L-sorbose was rapidly absorbed and partially metabolized while the principal pathway involved fermentation by the intestinal microflora to volatile fatty acids which were subsequently absorbed and metabolized. The total caloric utilization of L-sorbose was estimated to be 70%. It was observed that a human intestinal microflora also required an adaptation period in order to ferment this sugar. The efficiency of the fermentation was estimated to be 70%.
将L-[U-14C]-山梨糖以单剂量口服给予5只正常大鼠。放射性回收率在尿液中为5.3%，在粪便中为46%（仅以L-山梨糖形式），以二氧化碳形式为16%。热量利用率约为25%。第二组3只此前在饮食中摄入过L-山梨糖的大鼠，其14C回收率在尿液中为8.9%，在粪便中为6.6%，以二氧化碳形式为59%。呼出二氧化碳的时间进程表明，一部分L-山梨糖被快速吸收并部分代谢，而主要途径涉及肠道微生物群将其发酵为挥发性脂肪酸，随后这些脂肪酸被吸收并代谢。L-山梨糖的总热量利用率估计为70%。观察到人类肠道微生物群也需要一个适应期来发酵这种糖。发酵效率估计为70%。
