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The 3' noncoding region of beta-globin mRNA is not essential for in vitro translation.

作者信息

Kronenberg M N, Roberts B E, Efstratiadis A

出版信息

Nucleic Acids Res. 1979 Jan;6(1):153-66. doi: 10.1093/nar/6.1.153.

Abstract

Rabbit beta globin DNA sequence, excised from plasmid pbetaG1, directs in vitro synthesis of beta-globin in a transcription-translation cell-free system, even after specific elimination of the entire 3'-noncoding region. A DNA restriction fragment carrying this 3' noncoding region and hybridized to globin mRNA cannot arrest the cell-free translation of beta-globin mRNA.

摘要
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8dfe/327679/16f366544410/nar00442-0165-a.jpg

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