在先前接种过灭活病毒的豚鼠中接种活麻疹病毒后出现严重局部反应。
Severe local reaction following live measles virus in guinea pigs previously inoculated with killed virus.
作者信息
Matte V, Lussier G, Pavilania V, Ast O
出版信息
Can J Comp Med. 1969 Oct;33(4):261-3.
Abstract
Guinea pigs were immunized with inactivated measles virus. When challenged with live virus by the intradermal route, most of the animals developed an area of erythema within 24 to 48 hours; however, an unexpected feature of the skin-testing was that some of the guinea pigs developed a very severe necrotic reaction by the sixth or seventh day.
摘要
用灭活麻疹病毒对豚鼠进行免疫。当通过皮内途径用活病毒攻击时，大多数动物在24至48小时内出现红斑区域；然而，皮肤测试的一个意外特征是，一些豚鼠在第六天或第七天出现了非常严重的坏死反应。
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