• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利：CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法，用中文像聊天一样搜索，搜遍4000万医学文献。AI智能推荐，让科研检索更轻松。

立即免费搜索

文件翻译

保留排版，准确专业，支持PDF/Word/PPT等文件格式，支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述，25分钟生成高质量综述，智能提取关键信息，辅助科研写作。

立即免费体验

在先前接种过灭活病毒的豚鼠中接种活麻疹病毒后出现严重局部反应。

Severe local reaction following live measles virus in guinea pigs previously inoculated with killed virus.

作者信息

Matte V, Lussier G, Pavilania V, Ast O

出版信息

Can J Comp Med. 1969 Oct;33(4):261-3.

PMID:4243031
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC1319440/
Abstract

Guinea pigs were immunized with inactivated measles virus. When challenged with live virus by the intradermal route, most of the animals developed an area of erythema within 24 to 48 hours; however, an unexpected feature of the skin-testing was that some of the guinea pigs developed a very severe necrotic reaction by the sixth or seventh day.

摘要

用灭活麻疹病毒对豚鼠进行免疫。当通过皮内途径用活病毒攻击时，大多数动物在24至48小时内出现红斑区域；然而，皮肤测试的一个意外特征是，一些豚鼠在第六天或第七天出现了非常严重的坏死反应。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b34b/1319440/c14ce00c0714/compmed00068-0031-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b34b/1319440/8891cda09a2b/compmed00068-0030-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b34b/1319440/4413459787bc/compmed00068-0030-b.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b34b/1319440/c14ce00c0714/compmed00068-0031-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b34b/1319440/8891cda09a2b/compmed00068-0030-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b34b/1319440/4413459787bc/compmed00068-0030-b.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b34b/1319440/c14ce00c0714/compmed00068-0031-a.jpg

相似文献

1
Severe local reaction following live measles virus in guinea pigs previously inoculated with killed virus.在先前接种过灭活病毒的豚鼠中接种活麻疹病毒后出现严重局部反应。
Can J Comp Med. 1969 Oct;33(4):261-3.
2
Dissociation of erythema and basophil accumulation in Jones-Mote type hypersensitivity in the guinea-pig.豚鼠Jones-Mote型超敏反应中红斑与嗜碱性粒细胞聚集的分离
Br J Exp Pathol. 1979 Dec;60(6):596-603.
3
[Experience with the large-scale manufacture of a live associated mumps-measles vaccine].[大规模生产腮腺炎-麻疹联合减毒活疫苗的经验]
Tr Inst Im Pastera. 1979;53:89-94.
4
The problem of active immunization against measles.
J Hyg Epidemiol Microbiol Immunol. 1968;12(4):381-8.
5
Pathogenesis of vaccine strains of measles virus in suckling hamsters.麻疹病毒疫苗株在乳仓鼠中的致病机制。
Acta Virol. 1972 Jun;16(1):77-9.
6
Reactions to live-measles-virus vaccine in children previously inoculated with killed-virus vaccine.先前接种过灭活病毒疫苗的儿童对麻疹活病毒疫苗的反应。
N Engl J Med. 1967 Aug 3;277(5):248-50. doi: 10.1056/NEJM196708032770506.
7
Delayed-type hypersensitivity and in vitro lymphocyte response in guinea pigs immunized with a live varicella vaccine.用减毒水痘疫苗免疫的豚鼠的迟发型超敏反应和体外淋巴细胞反应
Biken J. 1984 Mar;27(1):19-22.
8
[Scientific basis and experience with the large-scale production of live measles vaccine L-16].
Vopr Virusol. 1969 Jan-Feb;14(1):13-8.
9
[Localization of specific antigen in the organs of animals inoculated with live measles vaccine].[接种活麻疹疫苗的动物器官中特异性抗原的定位]
Biull Eksp Biol Med. 1976 Oct;82(10):1232-4.
10
[Potency test of measles vaccines from inactivated viruses. II. Calculation by a new estimating formula].[灭活病毒麻疹疫苗的效价检测。II. 采用新估算公式进行计算]
Zentralbl Bakteriol Orig. 1968;207(2):158-65.

引用本文的文献

1
Arthus phenomenon like skin reaction and antibody pattern in rabbits immunized with various myxovirus fractions.用各种黏液病毒组分免疫的家兔中出现的类阿瑟斯现象皮肤反应及抗体模式。
Arch Gesamte Virusforsch. 1971;33(3):211-24. doi: 10.1007/BF01254677.

本文引用的文献

1
A REGIMEN FOR IMMUNIZATION AGAINST MEASLES. INACTIVATED VACCINE WITH DPT AND LIVE VACCINE AT AGE 9 MONTHS.
JAMA. 1965 Mar 29;191:1067-70. doi: 10.1001/jama.1965.03080130027008.
2
EPIDEMIOLOGIC STUDY OF INACTIVATED MEASLES VACCINE.灭活麻疹疫苗的流行病学研究
JAMA. 1964 Sep 7;189:723-8. doi: 10.1001/jama.1964.03070100017003.
3
Reactions to live-measles-virus vaccine in children previously inoculated with killed-virus vaccine.先前接种过灭活病毒疫苗的儿童对麻疹活病毒疫苗的反应。
N Engl J Med. 1967 Aug 3;277(5):248-50. doi: 10.1056/NEJM196708032770506.
4
Altered reactivity to measles virus: local reactions following attenuated measles virus immunization in children who previously received a combination of inactivated and attenuated vaccines.
Am J Dis Child. 1968 Jun;115(6):671-6. doi: 10.1001/archpedi.1968.02100010673006.
5
Delayed dermal hypersensitivity following killed measles vaccine. Experience in 9-month-old infants.
J Pediatr. 1967 Oct;71(4):525-9. doi: 10.1016/s0022-3476(67)80102-1.
6
Respiratory syncytial virus disease in infants despite prior administration of antigenic inactivated vaccine.尽管之前接种了抗原性灭活疫苗，但婴儿仍患呼吸道合胞病毒病。
Am J Epidemiol. 1969 Apr;89(4):422-34. doi: 10.1093/oxfordjournals.aje.a120955.
7
Development of delayed dermal hypersensitivity in guinea pigs immunized with inactivated respiratory syncytial virus vaccines.用灭活呼吸道合胞病毒疫苗免疫的豚鼠迟发型皮肤超敏反应的发展。
Proc Soc Exp Biol Med. 1968 Dec;129(3):777-82. doi: 10.3181/00379727-129-33423.