Turakulov Ia Kh, Saatov T S, Isaev E I, Sadykov S S, Zaĭnutdinov B R
Probl Endokrinol (Mosk). 1979 Mar-Apr;25(2):54-7.
The phospholipid spectrum and their content in the liver, heart, kidneys and the brain of rats was studied comparatively under normal conditions and in alloxan diabetes. Under pathological conditions there occurred significant changes in the amount of individual phospholipids in all the organs, but the most pronounced changes were noted in the brain. A sharp increase of cardiolipin content and a regular reduction of choline-containing lipids--lecithin and sphyngomyelin--in the organs under study were characteristic of alloxan diabetes. Oscillations in the concentration of other phospholipid fractions (phosphatidyl serine, phosphatidylinositol, phosphatidylethanolamine) had a definite organic specificity.
在正常条件下以及在四氧嘧啶糖尿病状态下，对大鼠肝脏、心脏、肾脏和大脑中的磷脂谱及其含量进行了比较研究。在病理条件下，所有器官中个别磷脂的含量均发生了显著变化，但大脑中的变化最为明显。在所研究的器官中，心磷脂含量急剧增加，而含胆碱的脂质（卵磷脂和鞘磷脂）则有规律地减少，这是四氧嘧啶糖尿病的特征。其他磷脂组分（磷脂酰丝氨酸、磷脂酰肌醇、磷脂酰乙醇胺）浓度的波动具有一定的器官特异性。
