Zhikhareva A I
Vopr Med Khim. 1979 Nov-Dec;25(6):673-6.
Phospholipid composition of rat liver tissue was distinctly altered in cooling. Single-term cooling caused a decrease in content of phosphatidic acids, cardiolipin, phosphatidyl diethanolamine, phosphatidyl serine but it increased the sphingomyelin level. Content of phosphatidyl choline and of lysolecithins was markedly decreased in short-term cooling. Prolonged cooling was accompanied by an increase in content of all the phospholipid fractions except of phosphatidyl choline. Appearance of monophosphoinositide in the phospholipid spectrum under all the conditions studied reflect the response of the organism to a stressing influence of cooling.
大鼠肝脏组织的磷脂组成在冷却过程中发生了明显变化。单次冷却导致磷脂酸、心磷脂、磷脂酰二乙醇胺、磷脂酰丝氨酸含量降低,但鞘磷脂水平升高。短期冷却时,磷脂酰胆碱和溶血卵磷脂的含量显著降低。长期冷却伴随着除磷脂酰胆碱外所有磷脂组分含量的增加。在所有研究条件下,磷脂谱中出现单磷酸肌醇反映了机体对冷却应激影响的反应。