Wetzner S M, Vincent M E, Robbins A H
Radiology. 1979 Apr;131(1):23-6. doi: 10.1148/131.1.23.
The cholecystokinetic effect of ceruletide, a synthetic decapeptide similar in action to cholecystokinin, was examined in both a randomized and nonrandomized study in 81 patients scheduled for routine oral cholecystograms. Intramuscular injection of ceruletide in a dose of 0.3 microgram/kg resulted in a mean maximum contraction of the gallbladder of 68% and a mean time until maximum contraction of 28 minutes. Visualization of the cystic duct occurred in 57 patients (70%); the common duct was seen in 67 (83%). Ceruletide demonstrated superior gallbladder contraction when compared to fatty meals and demonstrated no interference with a subsequent upper gastrointestinal series.
在一项针对81名计划进行常规口服胆囊造影的患者的随机和非随机研究中，检测了一种合成十肽——赛鲁肽（其作用与胆囊收缩素相似）的胆囊收缩作用。以0.3微克/千克的剂量肌肉注射赛鲁肽，胆囊平均最大收缩率为68%，达到最大收缩的平均时间为28分钟。57名患者（70%）的胆囊管显影；67名患者（83%）的胆总管显影。与脂肪餐相比，赛鲁肽显示出更好的胆囊收缩效果，并且对随后的上消化道造影检查没有干扰。
