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组织培养中胶质肿瘤细胞对酸性粘多糖的合成。

Synthesis of acid mucopolysaccharides by glial tumor cells in tissue culture.

作者信息

Dorfman A, Ho P L

出版信息

Proc Natl Acad Sci U S A. 1970 Jun;66(2):495-9. doi: 10.1073/pnas.66.2.495.

DOI:10.1073/pnas.66.2.495
PMID:4247492
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC283072/
Abstract

A clonal strain of rat glial tumor cells was shown to produce the acid mucopolysaccharides, hyaluronic acid, chondroitin 4-SO(4), and heparan sulfate in tissue culture. The mucopolysaccharides were isolated both from the growth medium and the cells.

摘要

一株大鼠胶质细胞瘤细胞克隆株在组织培养中被证明能产生酸性粘多糖、透明质酸、硫酸软骨素4 - SO(4)和硫酸乙酰肝素。这些粘多糖从生长培养基和细胞中都被分离出来。

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本文引用的文献

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Acid mucopolysaccharides of human brain: identification by means of infra-red analysis.人类大脑的酸性粘多糖：通过红外分析进行鉴定。
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Determination of 2-deoxy-2-sulfoaminohexose content of mucopolysaccharides.黏多糖中2-脱氧-2-磺氨基己糖含量的测定
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Method for the determination of hexosamines in tissues.组织中己糖胺的测定方法。
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The distribution and variation with age of different uronic acid-containing mucopolysaccharides in brain.脑中不同含糖醛酸粘多糖的分布及随年龄的变化
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The sulfation of chondroitin sulfate in embryonic chick cartilage epiphyses.胚胎期鸡软骨骨骺中硫酸软骨素的硫酸化作用。
J Biol Chem. 1969 Jan 25;244(2):348-52.
10
Differentiated rat glial cell strain in tissue culture.组织培养中的分化大鼠神经胶质细胞系。
Science. 1968 Jul 26;161(3839):370-1. doi: 10.1126/science.161.3839.370.