McAllister C J, Horn R, Havron S, Abramson J H
South Med J. 1979 Feb;72(2):162-5. doi: 10.1097/00007611-197902000-00015.
A 27-year-old man, a known heroin addict with previously diagnosed nephrotic syndrome, had a percutaneous renal biopsy for recurrent proteinuria. The biopsy revealed a glomerular lesion compatible with focal sclerosing hephropathy. The renal interstitium also demonstrated numerous active granulomas characterized by the presence of both multilamellated basophilic material and areas of unstained fibrillar material. These findings represent a previously undescribed complication of parenteral heroin abuse--renal granuloma formation.
一名27岁男性，已知为海洛因成瘾者，之前被诊断为肾病综合征，因蛋白尿复发接受经皮肾活检。活检显示肾小球病变符合局灶节段性肾小球硬化症。肾间质还可见大量活跃的肉芽肿，其特征为存在多层嗜碱性物质和未染色的纤维状物质区域。这些发现代表了一种先前未描述的静脉注射海洛因滥用并发症——肾肉芽肿形成。
