McCraw B M, Greenway J A
Can J Comp Med. 1970 Jul;34(3):247-55.
Gross changes in the lungs of Ascaris suum- infected calves consisted of atelectasis and hemorrhagic foci, edema and emphysema, frequently with bullae. Prominent microscopic lung lesions were edema and emphysema of the interlobular septa with large numbers of eosinophils within and around lymphatics, peribronchiolar lymphoid nodules and parasitic granulomas. Many of the microscopic features were consistent with those found in atypical interstitial pneumonia. Changes in the alveoli were atelectasis, the exudation of plasma proteins, mononuclear cells and eosinophils, and alveolar wall thickening. Lesions found later included fibrosis and fetalization of the alveolar walls. Plasma cells and neutrophils were not common. Challenge with Toxocara canis after sensitization with A. suum resulted in the lungs developing a few areas of atelectasis. Migration of T. canis to lungs of calves is slower than A. suum. A. suum larvae were always found in bronchi, bronchioles and alveoli of calves that died. Lesions were observed in the liver but not the kidney of A. suum infected calves; both lung and liver lesions tended to resolve with time.
感染猪蛔虫的犊牛肺部的大体变化包括肺不张和出血灶、水肿和气肿，常伴有大疱。显著的微观肺部病变为小叶间隔的水肿和气肿，淋巴管内及周围有大量嗜酸性粒细胞、支气管周围淋巴小结和寄生性肉芽肿。许多微观特征与非典型间质性肺炎中发现的特征一致。肺泡的变化为肺不张、血浆蛋白、单核细胞和嗜酸性粒细胞渗出以及肺泡壁增厚。后期发现的病变包括肺泡壁纤维化和胎儿化。浆细胞和中性粒细胞并不常见。在用猪蛔虫致敏后再用犬弓首蛔虫攻击，犊牛肺部会出现一些肺不张区域。犬弓首蛔虫向犊牛肺部的移行比猪蛔虫慢。在死亡的犊牛的支气管、细支气管和肺泡中总能发现猪蛔虫幼虫。在感染猪蛔虫的犊牛的肝脏中观察到病变，但肾脏未出现病变；随着时间的推移，肺部和肝脏病变都倾向于消退。
