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1968年在印度坎普尔发生的一起伴有出血表现的发热性疾病流行的临床与流行病学研究。

A clinical and epidemiological study of an epidemic of febrile illness with haemorrhagic manifestations which occurred at Kanpur, India, in 1968.

作者信息

Chaturvedi U C, Kapoor A K, Mathur A, Chandra D, Khan A M, Mehrotra R M

出版信息

Bull World Health Organ. 1970;43(2):281-7.

PMID:4249614
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC2427638/
Abstract

An epidemic of febrile illness associated with haemorrhagic manifestations and shock occurred at Kanpur, India, during 1968. The epidemic was widespread in the city, involving about one-tenth of the population; cases were more frequent in thickly populated localities with poor sanitary conditions. Those affected were mainly adolescents and adults of both sexes and multiple cases occurred in families. The disease was characterized by the sudden onset of fever, associated with severe headache and low backache. A number of patients had bradycardia, vomiting and diarrhoea and macular skin rashes associated with itching. A small percentage of the patients had haemorrhagic manifestations in the form of haematemesis, haemoptysis, melaena, haematuria and bleeding per vaginum. The mortality was very low. Dengue type 4 virus has been implicated in the epidemic.

摘要

1968年,印度坎普尔发生了一场伴有出血症状和休克的发热性疾病疫情。该疫情在城市中广泛传播,约十分之一的人口受到影响;在卫生条件差的人口密集地区病例更为频繁。受影响的主要是青少年和成年男女,家庭中出现多例病例。该病的特点是突然发热,伴有严重头痛和腰痛。一些患者出现心动过缓、呕吐、腹泻以及伴有瘙痒的斑疹。一小部分患者有呕血、咯血、黑便、血尿和阴道出血等出血表现。死亡率很低。此次疫情与4型登革热病毒有关。

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本文引用的文献

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VIROLOGICAL AND SEROLOGICAL STUDIES OF CASES OF HAEMORRHAGIC FEVER IN CALCUTTA: MATERIAL COLLECTED BY THE INSTITUTE OF POST-GRADUATE MEDICAL EDUCATION AND RESEARCH, CALCUTTA.加尔各答出血热病例的病毒学和血清学研究:由加尔各答研究生医学教育与研究学院收集的材料
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Virological study of an epidemic of febrile illness with haemorrhagic manifestations at Kanpur, India, during 1968.1968年印度坎普尔一场伴有出血症状的发热性疾病流行的病毒学研究。
Bull World Health Organ. 1970;43(2):289-93.