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[不同年龄大鼠肝脏和肾脏组织中的多胺浓度]

[Polyamine concentrations in the liver and kidney tissues of rats of different ages].

作者信息

Berdinskikh N K, Lialiushko N M

出版信息

Ukr Biokhim Zh (1978). 1979 Jan-Feb;51(1):73-5.

PMID:425143
Abstract

The spermidine and spermine contents in the liver and kidney tissues were determined for rats of different age. The age peculiarities in the polyamine content are revealed in the rat liver and are not observed in the kidneys. Spermidine prevails in the young rat liver, but spermine in the adult rat liver. The spermidine content in the young rat liver calculating per 1 g of fresh weight or per 1 mg of RNA is on the average twice as high as in adult animals. Spermine prevails in kidneys of both the growing and adult animals. The age peculiarities of the polyamine content in the liver are supposed to be connected with its protein-synthetizing function: the spermidine high content may be due to rapid synthesis of extracellular proteins which are necessary to the growing organism.

摘要

测定了不同年龄大鼠肝脏和肾脏组织中的亚精胺和精胺含量。在大鼠肝脏中发现了多胺含量的年龄特异性,而在肾脏中未观察到。亚精胺在幼鼠肝脏中占主导,但在成年大鼠肝脏中精胺占主导。按每1克鲜重或每1毫克RNA计算,幼鼠肝脏中的亚精胺含量平均是成年动物的两倍。精胺在生长中和成年动物的肾脏中占主导。肝脏中多胺含量的年龄特异性可能与其蛋白质合成功能有关:亚精胺的高含量可能是由于生长中的生物体所需的细胞外蛋白质的快速合成。

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