调节粗糙脉孢菌生长的黏多糖。
Mucopolysaccharide which regulates growth in Neurospora.
作者信息
Reissig J L, Glasgow J E
出版信息
J Bacteriol. 1971 Jun;106(3):882-9. doi: 10.1128/jb.106.3.882-889.1971.
Abstract
Neurospora produces a mucopolysaccharide (called MP) which inhibits its growth, causes vacuolation and agglutination of its cells, and precipitates its purified membrane protein. Cultures of a colonial strain display a phase of slow growth; the induction of this phase is traced to the production of MP by the mold. Stationary-phase cultures of wild type also produce MP. MP is a polymer of galactosamine, its amino groups only partially acetylated, probably containing other minor components. MP molecular weight is approximately 10(6). Complete acetylation abolishes the biological activities of MP. It is suggested that the regulatory effect of MP is mediated by its interaction with the protoplasmic membrane.
摘要
粗糙脉孢菌产生一种粘多糖（称为MP），它会抑制自身生长，导致细胞空泡化和凝集，并使纯化的膜蛋白沉淀。一个菌落菌株的培养物呈现出缓慢生长阶段；该阶段的诱导可追溯到霉菌产生的MP。野生型的稳定期培养物也会产生MP。MP是半乳糖胺的聚合物，其氨基仅部分乙酰化，可能还含有其他次要成分。MP的分子量约为10⁶。完全乙酰化会消除MP的生物活性。有人认为MP的调节作用是通过其与原生质膜的相互作用介导的。
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