氨甲蝶呤和5-氟脱氧尿苷对海拉细胞中三磷酸胸苷水平无影响。 - Suppr

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超能文献

Absence of an effect of amethopterin and 5-fluorodeoxyuridine upon levels of thymidine triphosphate in HeLa cells.

作者信息

Baumunk C N, Friedman D L

出版信息

Cancer Res. 1971 Dec;31(12):1930-5.

PMID:4256277

Abstract

摘要

相似文献

Absence of an effect of amethopterin and 5-fluorodeoxyuridine upon levels of thymidine triphosphate in HeLa cells.氨甲蝶呤和5-氟脱氧尿苷对海拉细胞中三磷酸胸苷水平无影响。

Cancer Res. 1971 Dec;31(12):1930-5.

Effect of methotrexate on deoxyribonucleotide pools and DNA synthesis in human lymphocytic cells.甲氨蝶呤对人淋巴细胞中脱氧核糖核苷酸库及DNA合成的影响。

Cancer Res. 1974 Aug;34(8):1883-8.

Effect of methotrexate and 5-fluorodeoxyuridine on ribonucleotide reductase activity in mammalian cells.甲氨蝶呤和5-氟脱氧尿苷对哺乳动物细胞中核糖核苷酸还原酶活性的影响。

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The regulation of thymidylate biosynthesis in Novikoff hepatoma cells and the effects of amethopterin, 5-fluorodeoxyuridine, and 3-deazauridine.诺维科夫肝癌细胞中胸苷酸生物合成的调节以及氨甲蝶呤、5-氟脱氧尿苷和3-去氮尿苷的作用。

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[A proof of the entrance of cells into the period of DNA synthesis under the effects of 5-fuoro-2'-desoxyuridine and amethopterin].[关于在5-氟-2'-脱氧尿苷和氨甲蝶呤作用下细胞进入DNA合成期的证据]

Dokl Akad Nauk SSSR. 1968 Jul 11;181(2):463-6.

Selective expansion of mitochondrial nucleoside triphosphate pools in antimetabolite-treated HeLa cells.抗代谢物处理的HeLa细胞中线粒体核苷三磷酸池的选择性扩张。

J Biol Chem. 1982 Aug 25;257(16):9300-4.

Amino acid requirement for fibroma virus replication in rabbit kidney cells.

Am J Vet Res. 1973 Feb;34(2):261-5.

Tetrahydrodeoxyuridylate: a potent inhibitor of deoxycytidylate deaminase.四氢脱氧尿苷酸：一种脱氧胞苷酸脱氨酶的强效抑制剂。

Arch Biochem Biophys. 1971 Jun;144(2):723-9. doi: 10.1016/0003-9861(71)90379-1.

Phleomycin stimulation of thymidine triphosphate incorporation by animal cell nuclei.博来霉素对动物细胞核掺入三磷酸胸苷的刺激作用。

J Natl Cancer Inst. 1974 Mar;52(3):693-7. doi: 10.1093/jnci/52.3.693.

[5-fluorodeoxyuridine induces radioresistant synthesis of DNA and sensitizes HeLa cells to gamma radiation].[5-氟脱氧尿苷诱导DNA的抗辐射合成并使HeLa细胞对γ辐射敏感]

Radiobiologiia. 1985 Sep-Oct;25(5):593-7.

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DNA synthesis in cytokinin-autotrophic tobacco cells : Effect of bromodeoxyuridine, fluorodeoxyuridine, and kinetin.细胞分裂素自养型烟草细胞中的 DNA 合成：溴脱氧尿苷、氟脱氧尿苷和激动素的影响。

Planta. 1981 Jul;152(3):215-24. doi: 10.1007/BF00385147.

Studies on the mechanism of fluoropyrimidine cytotoxicity in l1210 cells: correlation with inhibition of thymidylate synthetase but not with incorporation into RNA.研究氟嘧啶类药物在 L1210 细胞中的细胞毒性机制：与胸苷酸合成酶的抑制相关，但与 RNA 掺入无关。

Pharm Res. 1984 May;1(3):110-5. doi: 10.1023/A:1016371802607.

Metabolism of thymine nucleotides synthesized via the 'de novo' mechanism in normal, megaloblastic and methotrexate-treated human cells and in a lymphoblastoid cell line.在正常、巨幼细胞性和甲氨蝶呤处理的人类细胞以及一种淋巴母细胞样细胞系中，通过“从头合成”机制合成的胸腺嘧啶核苷酸的代谢。

Biochem J. 1981 Apr 15;196(1):225-35. doi: 10.1042/bj1960225.

Alternative metabolic fates of thymine nucleotides in human cells.人类细胞中胸腺嘧啶核苷酸的其他代谢命运。

Biochem J. 1981 Feb 15;194(2):451-61. doi: 10.1042/bj1940451.

Combined antiviral effect of DNA inhibitors on Herpes simplex virus multiplication.DNA抑制剂对单纯疱疹病毒增殖的联合抗病毒作用。

Med Microbiol Immunol. 1980;168(3):179-90. doi: 10.1007/BF02122852.

Inhibition of cell division by interferons. The relationship between changes in utilization of thymidine for DNA synthesis and control of proliferation in Daudi cells.干扰素对细胞分裂的抑制作用。达乌迪细胞中用于DNA合成的胸腺嘧啶核苷利用变化与增殖控制之间的关系。

Biochem J. 1983 Sep 15;214(3):983-90. doi: 10.1042/bj2140983.

Unbalanced deoxyribonucleotide synthesis caused by methotrexate.甲氨蝶呤导致的脱氧核糖核苷酸合成失衡。

Br Med J. 1972 May 13;2(5810):408. doi: 10.1136/bmj.2.5810.408.

Changes in the pyrimidine deoxynucleoside triphosphate pools of L5178Y cells after their exposure to methotrexate and 5-fluorouracil.L5178Y细胞暴露于甲氨蝶呤和5-氟尿嘧啶后嘧啶脱氧核苷三磷酸池的变化。

Biochem J. 1972 Sep;129(3):48P-49P. doi: 10.1042/bj1290048pb.

A model for compartmentation of de novo and salvage thymidine nucleotide pools in mammalian cells.哺乳动物细胞中从头合成和补救途径胸苷核苷酸池的区室化模型。

Proc Natl Acad Sci U S A. 1975 Sep;72(9):3333-6. doi: 10.1073/pnas.72.9.3333.

The fluoropyrimidines: biochemical mechanisms and design of clinical trials.氟嘧啶类药物：生化机制与临床试验设计

Cancer Chemother Pharmacol. 1978;1(2):77-82. doi: 10.1007/BF00254040.

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