Plato C C, Norris A H
Am J Epidemiol. 1979 Feb;109(2):169-80. doi: 10.1093/oxfordjournals.aje.a112672.
The left hand of each of 903 white males, most of them well-educated professionals, was evaluated for osteoarthritis, in the ongoing Baltimore Longitudinal Study of the Gerontology Research Center. The results of the joint-digit prevalence study indicated that: 1) the prevalence of osteoarthritis varies from one digit to the other; 2) osteoarthritis is considerably more prevalent in the distal than the proximal interphalangeal joints, regardless of digit or age group; 3) this disease is not only more prevalent in the distal interphalangeal joints, but it usually appears in a more severe form in the distal than in the proximal interphalangeal or the metacarpophalangeal joints. 4) Assuming that the presence of osteoarthritis in one joint is independent of the presence of the disease in the other joint of the same digit, there is an excess of digits with osteoarthritis in both the distal and proximal interphalangeal joints. This is suggestive of either a common etiology or that the presence of the disease in one joint enhances the development of osteoarthritis in the other joint of the same digit.
在正在进行的老年学研究中心巴尔的摩纵向研究中，对903名白人男性的左手进行了骨关节炎评估，他们大多数是受过良好教育的专业人士。关节指骨患病率研究结果表明：1）骨关节炎的患病率因手指不同而有所差异；2）无论手指或年龄组如何，远端指间关节的骨关节炎患病率均远高于近端指间关节；3）这种疾病不仅在远端指间关节更为普遍，而且通常在远端指间关节比在近端指间关节或掌指关节表现得更为严重。4）假设同一手指一个关节存在骨关节炎与该手指另一关节存在骨关节炎无关，那么在远端和近端指间关节中都存在骨关节炎的手指数量过多。这表明要么存在共同病因，要么同一手指一个关节存在该疾病会促进另一关节骨关节炎的发展。
