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培养的胸膜间皮细胞对温石棉纤维的吞噬作用。

Phagocytosis of chrysotile fibers by pleural mesothelial cells in culture.

作者信息

Jaurand M C, Kaplan H, Thiollet J, Pinchon M C, Bernaudin J F, Bignon J

出版信息

Am J Pathol. 1979 Mar;94(3):529-38.

Abstract

Pleural mesothelial cells (PMC) from the parietal pleura of rats were incubated in culture with UICC A chrysotile fibers. The sequence of events in phagocytosis was studied by electron microscopy: phases of attachment sequestration, and degranulation of lysosomal content into the phagocytic vacuole were observed. This demonstrates that PMC can engage in phagocytosis of chrysotile fibers.

摘要

将大鼠壁层胸膜的胸膜间皮细胞(PMC)与国际抗癌联盟(UICC)A类温石棉纤维一起进行培养。通过电子显微镜研究吞噬作用的一系列事件:观察到附着、隔离以及溶酶体内容物向吞噬泡脱颗粒的阶段。这表明PMC能够参与温石棉纤维的吞噬作用。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f1b0/2042260/5a3a2f095b43/amjpathol00247-0092-a.jpg

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