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大鼠去势前后附睾上皮细胞的差异吸收活性。

The differential absorptive activity of epithelial cells of the rat epididymus before and after castration.

作者信息

Moore H D, Bedford J M

出版信息

Anat Rec. 1979 Feb;193(2):313-27. doi: 10.1002/ar.1091930210.

DOI:10.1002/ar.1091930210
PMID:426301
Abstract

Horseradish peroxidase introduced into the lumen of the rat epididymis was taken up by the columnar cells of the epithelium by five minutes and more so after longer periods. The apical cells and particularly the clear cells in the caput and cauda epididymis, respectively, showed significantly greater endocytotic activity than the principal cell in both locations. Within 14 days after castration, however, such differences in absorptive activity among the various cell types were essentially obscured because of increased endocytosis by the androgen-deficient principal cells. The results are discussed briefly in terms of the function of different epithelial cell types and secretory/absorptive activity in the epididymis.

摘要

注入大鼠附睾管腔的辣根过氧化物酶在5分钟时被上皮柱状细胞摄取,较长时间后摄取更多。附睾头和附睾尾的顶端细胞,特别是透明细胞,在这两个部位的内吞活性均明显高于主细胞。然而,去势后14天内,由于雄激素缺乏的主细胞内吞作用增强,不同细胞类型之间的这种吸收活性差异基本消失。根据附睾中不同上皮细胞类型的功能以及分泌/吸收活性对结果进行了简要讨论。

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