Matthews T H, Lawrence M K
Arch Virol. 1979;59(1-2):35-8. doi: 10.1007/BF01317892.
Acute phase serum gave positive results in an interferon assay when collected from 17 out of 45 (38 per cent) patients with proven virus infection, and from none of 43 patients with other disease and none of 61 healthy subjects. Sera from 11 of 43 (26 per cent) patients with suspected virus infection were also positive. Interferon was detected in the sera of volunteers infected with respiratory viruses in strict isolation. It is suggested that the test might be used to supplement conventional tests for virus infections, and with modification may provide a useful diagnostic aid.
在45例经证实有病毒感染的患者中,有17例(38%)急性期血清在干扰素检测中呈阳性结果,而43例患有其他疾病的患者及61例健康受试者的血清均为阴性。43例疑似病毒感染患者中有11例(26%)血清也呈阳性。在严格隔离的感染呼吸道病毒的志愿者血清中检测到了干扰素。有人提出该检测可用于补充病毒感染的传统检测方法,并且经过改进可能会成为一种有用的诊断辅助手段。