Yamada T, Stevland N, Kimura J
Arch Neurol. 1979 Apr;36(4):225-7. doi: 10.1001/archneur.1979.00500400079013.
An EEG of a two-year-old child with Reye's syndrome complicated by prolonged hypoglycemia showed continuous, diffusely distributed, 8- to 9-Hz, well-modulated alpha activity while the patient was comatose. Continuous monitoring of EEG showed gradual reduction of alpha activity and the appearance of moderate-amplitude delta waves within the next 18 hours. Subsequent EEGs showed electrocerebral silence. The EEG features and their evolution resembled those described in postanoxic "alpha-pattern coma" in adults. A diffuse cortical-subcortical insult, possibly due to hypoglycemia, may be responsible for the generation of diffuse alpha activity in our case. Because of its transient nature, immediate and serial EEG studies following the acute cerebral insult may be necessary to demonstrate this pattern in children.
一名患有瑞氏综合征并伴有持续性低血糖的两岁儿童的脑电图显示，在患者昏迷期间，存在持续的、弥漫分布的、8至9赫兹、调制良好的阿尔法波活动。脑电图的持续监测显示，在接下来的18小时内，阿尔法波活动逐渐减少，出现了中等幅度的德尔塔波。随后的脑电图显示脑电静息。脑电图特征及其演变与成人缺氧后“阿尔法波昏迷模式”中所描述的相似。在我们的病例中，可能由于低血糖导致的弥漫性皮质-皮质下损伤，可能是产生弥漫性阿尔法波活动的原因。由于其短暂性，在急性脑损伤后立即进行系列脑电图研究，对于在儿童中证实这种模式可能是必要的。
