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猪白细胞中E组链球菌的体外研究。II. 免疫和非免疫猪巨噬细胞的吞噬和杀菌特性。

In vitro studies of group E streptococci in swine leukocytes. II. Phagocytic and bactericidal properties of macrophages from immune and nonimmune swine.

作者信息

Cargill C F, Olson L D

出版信息

Can J Comp Med. 1973 Apr;37(2):112-5.

Abstract

Macrophages collected from susceptible swine and grown in nonimmune serum phagocytized and digested group E Streptococci (GES). However, macrophages collected from immune swine and grown in nonimmune serum were capable of much higher rates of phagocytosis and intracellular digestion of the organism. The addition of immune serum to cultures of immune macrophages increased the rate of phagocytosis but not the rate of intracellular digestion of GES by the macrophages. These findings are discussed in relation to mechanisms of cellular immunity.

摘要

从易感猪采集并在非免疫血清中培养的巨噬细胞吞噬并消化了E组链球菌(GES)。然而,从免疫猪采集并在非免疫血清中培养的巨噬细胞对该生物体的吞噬和细胞内消化率要高得多。向免疫巨噬细胞培养物中添加免疫血清可提高吞噬率,但不能提高巨噬细胞对GES的细胞内消化率。结合细胞免疫机制对这些发现进行了讨论。

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