Dymond D S, Jarritt P H, Britton K E, Spurrell R A
Br Heart J. 1979 Jan;41(1):68-78. doi: 10.1136/hrt.41.1.68.
Eighteen patients with a history of previous anterior myocardial infarction and suspected left ventricular aneurysms were studied both by contrast left ventriculography and by first pass radionuclide ventriculography using Technetium99m and a computerised multicrystal gamma camera. The radionuclide study successfully identified all 14 patients with aneurysms and all 4 with diffusely hypo-kinetic ventricles. Ejection fraction calculated from the change in radioactive counts in the left ventricle correlated well with that calculated from the area-length method from the contrast angiogram (r = 0.83). Ventricular volumes calculated from the area-length formula for both contrast and radionuclide angiograms correlated closely (r = 0.85 and r = 0.89 for end-systolic and end-diastolic volumes, respectively). In the patients with aneurysms, there was a close correlation between the extent of akinesis, as assessed by the two methods (r = 0.94). The ability of the radionuclide ventriculogram to provide accurate information on global and segmental ventricular function, and to differentiate between segmental and diffuse ventricular dysfunction, enables the method to act as a screening procedure in the investigation of patients with suspected left ventricular aneurysms.
对18例有陈旧性前壁心肌梗死病史且疑似左心室室壁瘤的患者，采用造影剂左心室造影以及使用锝99m和计算机化多晶体γ相机的首次通过放射性核素心室造影进行了研究。放射性核素研究成功识别出了所有14例室壁瘤患者以及所有4例左心室弥漫性运动减弱的患者。根据左心室内放射性计数变化计算出的射血分数与根据造影血管造影的面积-长度法计算出的射血分数相关性良好（r = 0.83）。根据造影和放射性核素血管造影的面积-长度公式计算出的心室容积密切相关（收缩末期容积和舒张末期容积的r分别为0.85和0.89）。在室壁瘤患者中，两种方法评估的运动不能程度之间存在密切相关性（r = 0.94）。放射性核素心室造影能够提供关于整体和节段性心室功能的准确信息，并区分节段性和弥漫性心室功能障碍，这使得该方法能够作为一种筛查程序用于疑似左心室室壁瘤患者的检查。
