极低出生体重儿动脉导管未闭对口服吲哚美辛治疗反应不佳。
Poor response to oral indomethacin therapy for persistent ductus arteriosus in very low birthweight infants.
作者信息
Cooke R W, Pickering D
出版信息
Br Heart J. 1979 Mar;41(3):301-3. doi: 10.1136/hrt.41.3.301.
Abstract
Administration of oral indomethacin to treat cardiorespiratory failure in 7 low birthweight infants, after failure of conventional therapy, produced an improvement in only 2 infants. These infants had a higher birthweight than the group as a whole. Surgical ligation, rather than oral indomethacin, may be the treatment of choice for persistent ductus arteriosus in very low birthweight infants.
摘要
在7名低体重儿常规治疗失败后，给予口服吲哚美辛治疗心肺功能衰竭，仅2名婴儿病情有所改善。这些婴儿的出生体重高于总体组。对于极低体重儿的持续性动脉导管未闭，手术结扎而非口服吲哚美辛可能是首选治疗方法。
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