Martens C L, Sargent M L
J Bacteriol. 1974 Mar;117(3):1210-5. doi: 10.1128/jb.117.3.1210-1215.1974.
Wild-type, band, and fluffy strains of Neurospora crassa exhibit circadian rhythms of ribonucleic acid and deoxyribonucleic acid content in the growth-front hyphae of cultures grown on a solid medium. There is also a rhythm of (3)H-uridine incorporation into the nucleic acids of the band strain. Maximum incorporation precedes the peaks of nucleic acid content which occur during conidiation. As cultures age, ribonucleic acid content decreases rapidly and deoxyribonucleic acid content decreases gradually in standing, shake, and bubble cultures. A reduction of ribonuclease activity with age is also noted in standing and shake cultures. The nucleic acid content, nuclease activity, and changes associated with age vary with the culture conditions.
野生型、带状和蓬松型粗糙脉孢菌菌株在固体培养基上生长的培养物的生长前沿菌丝中表现出核糖核酸和脱氧核糖核酸含量的昼夜节律。带状菌株的核酸中也存在（3）H-尿苷掺入的节律。最大掺入量先于分生孢子形成期间出现的核酸含量峰值。随着培养物老化，静置、振荡和气升式培养物中的核糖核酸含量迅速下降，脱氧核糖核酸含量逐渐下降。在静置和振荡培养物中也注意到核糖核酸酶活性随老化而降低。核酸含量、核酸酶活性以及与老化相关的变化随培养条件而变化。
