在与苯并(a)芘或二氢二醇环氧化物衍生物孵育的10T1/2小鼠胚胎成纤维细胞中DNA加合物的形成。 - Suppr

Suppr

超能文献

Formation of DNA adducts in 10T1/2 mouse embryo fibroblasts incubated with benzo(a)pyrene or dihydrodiol oxide derivatives.

作者信息

Brown H S, Jeffrey A M, Weinstein I B

出版信息

Cancer Res. 1979 May;39(5):1673-7.

PMID:427804

Abstract

摘要

相似文献

Formation of DNA adducts in 10T1/2 mouse embryo fibroblasts incubated with benzo(a)pyrene or dihydrodiol oxide derivatives.在与苯并(a)芘或二氢二醇环氧化物衍生物孵育的10T1/2小鼠胚胎成纤维细胞中DNA加合物的形成。

Cancer Res. 1979 May;39(5):1673-7.

Metabolism of benzo(a)pyrene by human epithelial and fibroblastic cells: metabolite patterns and DNA adduct formation.人上皮细胞和成纤维细胞对苯并(a)芘的代谢：代谢物模式与DNA加合物的形成

J Cell Biochem. 1982;18(2):135-48. doi: 10.1002/jcb.1982.240180202.

Analysis of benzo(a)pyrene:DNA adducts formed in cells in culture by immobilized boronate chromatography.通过固定化硼酸酯色谱法分析培养细胞中形成的苯并(a)芘:DNA加合物。

Cancer Res. 1984 Sep;44(9):4104-10.

Comparison of the cellular DNA-bound products of benzo(alpha)pyrene with the products formed by the reaction of benzo(alpha)pyrene-4,5-oxide with DNA.

Cancer Res. 1975 Jan;35(1):54-7.

Benzo(a)pyrene:DNA adduct formation in early-passage Wistar rat embryo cell cultures: evidence for multiple pathways of activation of benzo(a)pyrene.苯并（a）芘：早期传代的Wistar大鼠胚胎细胞培养物中DNA加合物的形成：苯并（a）芘多种活化途径的证据

Cancer Res. 1986 Feb;46(2):545-52.

Persistence of benzo(a)pyrene metabolite:DNA adducts in lung and liver of mice.苯并(a)芘代谢产物在小鼠肺和肝脏中DNA加合物的持久性。

Cancer Res. 1984 Jan;44(1):97-101.

Formation and persistence of DNA, RNA, and protein adducts in mouse skin exposed to pure optical enantiomers of 7 beta,8 alpha-dihydroxy-9 alpha,10 alpha-epoxy-7,8,9,10-tetrahydrobenzo(a)pyre ne in vivo.体内暴露于7β,8α-二羟基-9α,10α-环氧-7,8,9,10-四氢苯并(a)芘纯光学对映体的小鼠皮肤中DNA、RNA和蛋白质加合物的形成与持久性。

Cancer Res. 1984 Mar;44(3):1081-6.

Differential removal of DNA adducts derived from anti-diol epoxides of dibenzo[a,l]pyrene and benzo[a]pyrene in human cells.人细胞中源自二苯并[a,l]芘和苯并[a]芘反式二醇环氧化物的DNA加合物的差异去除

Chem Res Toxicol. 2005 Apr;18(4):655-64. doi: 10.1021/tx0497090.

Metabolism of benzo(a)pyrene in epidermal keratinocytes and dermal fibroblasts of humans and mice with reference to variation among species, individuals, and cell types.人与小鼠表皮角质形成细胞和真皮成纤维细胞中苯并(a)芘的代谢，涉及物种、个体及细胞类型间的差异

Cancer Res. 1982 May;42(5):1859-65.

Metabolism and formation of DNA adducts of benzo(a)pyrene in human diploid fibroblasts.苯并(a)芘在人二倍体成纤维细胞中的代谢及DNA加合物的形成

Cancer Res. 1979 Mar;39(3):1083-8.

引用本文的文献

Detection of chemical carcinogens by assay of unscheduled DNA synthesis in rat tracheal epithelium in short-term organ culture.通过短期器官培养中大鼠气管上皮细胞非程序性DNA合成检测化学致癌物。

J Cancer Res Clin Oncol. 1981;102(2):115-26. doi: 10.1007/BF00410663.

Error-free excision of the cytotoxic,mutagenic N2-deoxyguanosine DNA adduct formed in human fibroblasts by (+/-)-7 beta, 8 alpha-dihydroxy-9 alpha, 10 alpha-epoxy-7,8,9,10-tetrahydrobenzo[a]pyrene.人成纤维细胞中由（±）-7β，8α-二羟基-9α，10α-环氧-7,8,9,10-四氢苯并[a]芘形成的具有细胞毒性、致突变性的N2-脱氧鸟苷DNA加合物的无差错切除。

Proc Natl Acad Sci U S A. 1980 Oct;77(10):5933-7. doi: 10.1073/pnas.77.10.5933.

Interactions of chrysotile and benzopyrene in a human cell culture systems.温石棉与苯并芘在人类细胞培养系统中的相互作用。

Environ Health Perspect. 1983 Sep;51:257-65. doi: 10.1289/ehp.8351257.

Metabolism of benzo[a]pyrene by human mammary epithelial cells: toxicity and DNA adduct formation.人乳腺上皮细胞对苯并[a]芘的代谢：毒性与DNA加合物形成

Proc Natl Acad Sci U S A. 1981 Oct;78(10):6251-5. doi: 10.1073/pnas.78.10.6251.

Monoclonal antibodies to DNA modified by 8-methoxypsoralen and ultraviolet A light.针对经8-甲氧基补骨脂素和紫外线A光修饰的DNA的单克隆抗体。

Nucleic Acids Res. 1985 Apr 11;13(7):2533-44. doi: 10.1093/nar/13.7.2533.

Chemical carcinogens: a review of the science and its associated principles. U.S. Interagency Staff Group on Carcinogens.化学致癌物：科学及其相关原理综述。美国致癌物问题跨部门工作人员小组

Environ Health Perspect. 1986 Aug;67:201-82. doi: 10.1289/ehp.67-1474412.

Production of oxidative DNA damage during the metabolic activation of benzo[a]pyrene in human mammary epithelial cells correlates with cell killing.苯并[a]芘在人乳腺上皮细胞中代谢活化过程中产生的氧化性DNA损伤与细胞杀伤相关。

Proc Natl Acad Sci U S A. 1988 Jun;85(12):4365-8. doi: 10.1073/pnas.85.12.4365.

Effects of 5-azacytidine on the progressive nature of cell transformation.5-氮杂胞苷对细胞转化进展特性的影响。

Mol Cell Biol. 1985 Jul;5(7):1800-3. doi: 10.1128/mcb.5.7.1800-1803.1985.

Formation of benzo[a]pyrene-DNA adducts in blood monocytes from lung cancer patients with a familial history of lung cancer.有肺癌家族史的肺癌患者血液单核细胞中苯并[a]芘-DNA加合物的形成。

J Cancer Res Clin Oncol. 1992;118(1):67-71. doi: 10.1007/BF01192314.

文献检索

告别复杂PubMed语法，用中文像聊天一样搜索，搜遍4000万医学文献。AI智能推荐，让科研检索更轻松。

立即免费搜索

文件翻译

保留排版，准确专业，支持PDF/Word/PPT等文件格式，支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述，25分钟生成高质量综述，智能提取关键信息，辅助科研写作。

立即免费体验