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对氯苯丙氨酸处理后雄性去势大鼠的交配行为缺失

Lack of copulatory behaviour in male castrated rats after p-chlorophenylalanine.

作者信息

Del Fiacco M, Fratta W, Gessa G L, Tagliamonte A

出版信息

Br J Pharmacol. 1974 Jun;51(2):249-51. doi: 10.1111/j.1476-5381.1974.tb09654.x.

Abstract

1 The effect of p-chlorophenylalanine (PCPA) on the copulatory behaviour of normal and castrated male rats with females in oestrus was studied.2 Castration 2 months before the experiment completely prevented the increased copulatory behaviour produced by PCPA in normal rats.3 The administration of testosterone restored the copulatory behaviour in the castrated rats indicating that testosterone is essential for this behaviour.

摘要
  1. 研究了对氯苯丙氨酸(PCPA)对正常和去势雄性大鼠与处于发情期雌性交配行为的影响。

  2. 实验前2个月去势完全阻止了PCPA在正常大鼠中引起的交配行为增加。

  3. 给予睾酮恢复了去势大鼠的交配行为,表明睾酮对这种行为至关重要。

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本文引用的文献

3
Aphrodisiac effect of p-chlorophenylalanine.对氯苯丙氨酸的催情作用。
Science. 1971 Feb 19;171(3972):706. doi: 10.1126/science.171.3972.706.
4
"Hypersexuality" and behavioral changes in cats caused by administration of p-chlorophenylalanine.
Science. 1970 Apr 24;168(3930):499-501. doi: 10.1126/science.168.3930.499.
6
The effect of parachlorophenylalanine on the behaviour of cats.对氯苯丙氨酸对猫行为的影响。
Br J Pharmacol. 1970 Dec;40(4):659-67. doi: 10.1111/j.1476-5381.1970.tb10645.x.

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