• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

内分泌疾病中下丘脑 - 垂体功能的评估

Assessment of hypothalamic pituitary function in endocrine disease.

作者信息

Greenwood F C, Landon J

出版信息

J Clin Pathol. 1966 May;19(3):284-92. doi: 10.1136/jcp.19.3.284.

DOI:10.1136/jcp.19.3.284
PMID:4287115
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC473256/
Abstract

The insulin test carried out with adequate safeguards under standardized conditions yields valuable information regarding hypothalamic and pituitary function when plasma levels of sugar, cortisol, and growth hormone are determined. The use of a test based on the plasma cortisol response to the infusion of lysine-vasopressin, a polypeptide with a corticotrophin-releasing action, is also of value as a test of pituitary function. Used in conjunction with the insulin test it enables pituitary disorders to be differentiated from those involving the hypothalamus.

摘要

在标准化条件下并采取适当防护措施进行的胰岛素测试,在测定血糖、皮质醇和生长激素的血浆水平时,可提供有关下丘脑和垂体功能的有价值信息。基于血浆皮质醇对赖氨酸加压素输注的反应进行的测试也具有价值,赖氨酸加压素是一种具有促肾上腺皮质激素释放作用的多肽,可作为垂体功能测试。与胰岛素测试结合使用时,它能够将垂体疾病与涉及下丘脑的疾病区分开来。

相似文献

1
Assessment of hypothalamic pituitary function in endocrine disease.内分泌疾病中下丘脑 - 垂体功能的评估
J Clin Pathol. 1966 May;19(3):284-92. doi: 10.1136/jcp.19.3.284.
2
Plasma-cortisol response to lysine-vasopressin. Comparison with other tests of human pituitary-adrenocortical function.血浆皮质醇对赖氨酸加压素的反应。与人类垂体 - 肾上腺皮质功能的其他测试的比较。
Lancet. 1965 Dec 4;2(7423):1156-9. doi: 10.1016/s0140-6736(65)92560-2.
3
Plasma cortisol response to ACTH does not accurately indicate the state of hypothalamic-pituitary-adrenal axis.
J Endocrinol Invest. 1982 Jul-Aug;5(4):259-61. doi: 10.1007/BF03348333.
4
[Response of plasma cortisol to lysine-vasopressin administration. Comparative study with other hypothalamo-pituitary-adrenal function tests].[血浆皮质醇对赖氨酸加压素给药的反应。与其他下丘脑-垂体-肾上腺功能测试的比较研究]
Prensa Med Mex. 1970 May-Jun;35(5):213-7.
5
Evaluation of adrenal function in patients with growth hormone deficiency and hypothalamic-pituitary disorders: comparison between insulin-induced hypoglycemia, low-dose ACTH, standard ACTH and CRH stimulation tests.生长激素缺乏症和下丘脑 - 垂体疾病患者肾上腺功能的评估:胰岛素诱导低血糖试验、低剂量促肾上腺皮质激素试验、标准促肾上腺皮质激素试验和促肾上腺皮质激素释放激素刺激试验之间的比较
Eur J Endocrinol. 2005 May;152(5):735-41. doi: 10.1530/eje.1.01911.
6
Hypothalamic-pituitary-adrenal function in the elderly.老年人的下丘脑-垂体-肾上腺功能
Gerontol Clin (Basel). 1968;10(6):334-9. doi: 10.1159/000245201.
7
Hypothalamic-pituitary function tests: current status.下丘脑 - 垂体功能测试:现状
Postgrad Med. 1977 Nov;62(5):105-14. doi: 10.1080/00325481.1977.11714675.
8
Studies of the regulation of the hypothalamic-pituitary-adrenal axis in sheep with hypothalamic-pituitary disconnection. I. Effect of an audiovisual stimulus and insulin-induced hypoglycemia.下丘脑-垂体离断绵羊下丘脑-垂体-肾上腺轴调节的研究。I. 视听刺激和胰岛素诱导低血糖的影响。
Neuroendocrinology. 1988 Nov;48(5):551-60. doi: 10.1159/000125062.
9
Evaluation of three acute tests of hypothalamic-pituitary-adrenal function.
Metabolism. 1969 Jun;18(6):476-83. doi: 10.1016/0026-0495(69)90140-1.
10
The assessment of the functional capacity of the hypothalamic-pituitary-adrenal axis by measurement of basal plasma and urinary cortisol in comparison with insulin-induced hypoglycaemia and metyrapone tests.通过测量基础血浆和尿皮质醇,并与胰岛素诱导的低血糖和甲吡酮试验相比较,评估下丘脑 - 垂体 - 肾上腺轴的功能能力。
Neth J Med. 1993 Aug;43(1-2):64-8.

引用本文的文献

1
Copeptin as a marker of an altered CRH axis in pituitary disease. copeptin 作为垂体疾病中 CRH 轴改变的标志物。
Endocrine. 2017 Sep;57(3):474-480. doi: 10.1007/s12020-017-1366-6. Epub 2017 Aug 9.
2
Blood-glucose, plasma-insulin and growth hormone concentrations of individuals with minor abnormalities of glucose tolerance.糖耐量轻度异常个体的血糖、血浆胰岛素和生长激素浓度。
Diabetologia. 1968 Mar;4(2):73-82. doi: 10.1007/BF01212536.
3
Growth hormone secretion during sleep.睡眠期间的生长激素分泌。
J Clin Invest. 1968 Sep;47(9):2079-90. doi: 10.1172/JCI105893.
4
Endocrine disturbances in childhood obesity: growth-hormone and cortisol response to insulin induced hypoglycemia.
Klin Wochenschr. 1972 Jul 15;50(14):706-10. doi: 10.1007/BF01495530.
5
Hypothalamic and pituitary injury.
J Clin Pathol Suppl (R Coll Pathol). 1970;4:178-86. doi: 10.1136/jcp.s3-4.1.178.
6
[Regulation of somatotropin secretion: attempted unitary interpretation].[生长激素分泌的调节:统一解释的尝试]
Acta Diabetol Lat. 1973 Jan-Feb;10(1):91-106. doi: 10.1007/BF02590653.
7
Role of glucagon, catecholamines, and growth hormone in human glucose counterregulation. Effects of somatostatin and combined alpha- and beta-adrenergic blockade on plasma glucose recovery and glucose flux rates after insulin-induced hypoglycemia.胰高血糖素、儿茶酚胺和生长激素在人体葡萄糖反向调节中的作用。胰岛素诱导低血糖后,生长抑素以及α和β肾上腺素能联合阻断对血浆葡萄糖恢复和葡萄糖通量率的影响。
J Clin Invest. 1979 Jul;64(1):62-71. doi: 10.1172/JCI109464.
8
The role of adrenergic mechanisms in the substrate and hormonal response to insulin-induced hypoglycemia in man.肾上腺素能机制在人体对胰岛素诱导的低血糖的底物和激素反应中的作用。
J Clin Invest. 1976 Jul;58(1):7-15. doi: 10.1172/JCI108460.

本文引用的文献

1
Neural control of the pituitary gland. II. The adenohypophysis, with special reference to the secretion of A.C.T.H.垂体的神经控制。II. 腺垂体,特别涉及促肾上腺皮质激素的分泌
Br Med J. 1951 Sep 15;2(4732):627-34. doi: 10.1136/bmj.2.4732.627.
2
A simple fluorimetric method for the estimation of free 11-hydroxycorticoids in human plasma.一种用于测定人血浆中游离11-羟基皮质类固醇的简易荧光法。
J Clin Pathol. 1962 Jul;15(4):374-9. doi: 10.1136/jcp.15.4.374.
3
Clinical application of a new test of pituitary reserve.垂体储备新检测方法的临床应用
J Clin Endocrinol Metab. 1959 Aug;19:875-94. doi: 10.1210/jcem-19-8-875.
4
PLASMA GROWTH HORMONE RESPONSE TO INTRAVENOUS ADMINISTRATION OF AMINO ACIDS.血浆生长激素对静脉注射氨基酸的反应。
J Clin Endocrinol Metab. 1965 Aug;25:1140-4. doi: 10.1210/jcem-25-8-1140.
5
ADRENAL RESPONSE TO INFUSED CORTICOTROPIN IN SUBJECTS RECEIVING GLUCOCORTICOIDS.接受糖皮质激素治疗的受试者对注入促肾上腺皮质激素的肾上腺反应。
J Clin Endocrinol Metab. 1965 May;25:602-11. doi: 10.1210/jcem-25-5-602.
6
RADIOIMMUNOASSAY OF HUMAN PLASMA ACTH.人血浆促肾上腺皮质激素的放射免疫测定
J Clin Endocrinol Metab. 1964 Nov;24:1219-25. doi: 10.1210/jcem-24-11-1219.
7
HUMAN GROWTH HORMONE. CLINICAL MEASUREMENT, RESPONSE TO HYPOGLYCEMIA AND SUPPRESSION BY CORTICOSTEROIDS.人类生长激素。临床测量、对低血糖的反应及皮质类固醇的抑制作用
N Engl J Med. 1964 Dec 31;271:1375-81. doi: 10.1056/NEJM196412312712701.
8
EFFECT OF CORTICOSTEROIDS ON SERUM GROWTH HORMONE.皮质类固醇对血清生长激素的影响。
Lancet. 1964 Aug 22;2(7356):376-8. doi: 10.1016/s0140-6736(64)90389-7.
9
GROWTH-HORMONE LEVELS IN CHILDREN AND ADOLESCENTS.儿童和青少年的生长激素水平
Br Med J. 1964 Jan 4;1(5374):25-6. doi: 10.1136/bmj.1.5374.25.
10
IMMUNOASSAY OF HUMAN GROWTH HORMONE IN PLASMA.血浆中人生长激素的免疫测定
Nature. 1963 Aug 24;199:784-7. doi: 10.1038/199784a0.