内分泌疾病中下丘脑 - 垂体功能的评估
Assessment of hypothalamic pituitary function in endocrine disease.
作者信息
Greenwood F C, Landon J
出版信息
J Clin Pathol. 1966 May;19(3):284-92. doi: 10.1136/jcp.19.3.284.
Abstract
The insulin test carried out with adequate safeguards under standardized conditions yields valuable information regarding hypothalamic and pituitary function when plasma levels of sugar, cortisol, and growth hormone are determined. The use of a test based on the plasma cortisol response to the infusion of lysine-vasopressin, a polypeptide with a corticotrophin-releasing action, is also of value as a test of pituitary function. Used in conjunction with the insulin test it enables pituitary disorders to be differentiated from those involving the hypothalamus.
摘要
在标准化条件下并采取适当防护措施进行的胰岛素测试，在测定血糖、皮质醇和生长激素的血浆水平时，可提供有关下丘脑和垂体功能的有价值信息。基于血浆皮质醇对赖氨酸加压素输注的反应进行的测试也具有价值，赖氨酸加压素是一种具有促肾上腺皮质激素释放作用的多肽，可作为垂体功能测试。与胰岛素测试结合使用时，它能够将垂体疾病与涉及下丘脑的疾病区分开来。
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