一种作用于L-酪氨酸O-硫酸酯的大鼠组织转氨酶。
A rat-tissue aminotransferase acting on L-tyrosine O-sulphate.
作者信息
Rose F A, Flanagan T H, John R A
出版信息
Biochem J. 1966 Jan;98(1):168-72. doi: 10.1042/bj0980168.
Abstract
- Rat tissues have been shown to possess an aminotransferase that is active towards l-tyrosine O-sulphate and dependent on 2-oxoglutarate and pyridoxal phosphate. 2. Kidney, liver and pancreas have the greatest activity and the enzyme is localized mainly in the mitochondrial fraction in the liver and kidney cell. 3. The enzyme was shown to be distinct from l-tyrosine-2-oxoglutarate aminotransferase but its true identity was not established. 4. A procedure for the assay of the enzyme in crude tissue preparations was developed.
摘要
- 已证明大鼠组织中存在一种对L-酪氨酸O-硫酸盐有活性且依赖于2-氧代戊二酸和磷酸吡哆醛的转氨酶。2. 肾脏、肝脏和胰腺的活性最高，该酶主要定位于肝细胞和肾细胞的线粒体部分。3. 该酶被证明与L-酪氨酸-2-氧代戊二酸转氨酶不同，但其确切身份尚未确定。4. 开发了一种在粗制组织制剂中测定该酶的方法。
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